DNA double-strand breaks (DSBs) are deleterious DNA lesions that if left unrepaired or are
misrepaired, potentially result in chromosomal aberrations, known drivers of carcinogenesis …

Objective Oral squamous cell carcinoma has a remarkable incidence worldwide and a fairly
onerous prognosis, encouraging further research on factors that might modify disease …

Objectives In this review paper, we explored the application of “omics” approaches in the
study of oral cancer (OC). It will provide a better understanding of how “omics” approaches …

Cells experience both endogenous and exogenous DNA damage daily. To maintain
genome integrity and suppress tumorigenesis, individuals have evolutionarily acquired a …

Oral cancer is a malignant neoplasia that is more common in Asian than other regions, and
men are at higher risk than women. Currently, clinical treatment for oral cancer consists of …

Numerous studies have demonstrated that autophagy is associated with cancer
development. Thus, agents to induce autophagy could be employed in some cases for the …

Introduction: Normal function of DNA repair system is essential for the removal of damage
induced by many kinds of internal and environmental agents. Genetic polymorphisms in …

The aim of this study was to estimate the relations between hypoxia inducible factor-1α (HIF-
1α) gene polymorphisms, C1772T and G1790A, to the susceptibility and clinicopathological …

Abstract Objectives/Hypothesis: The ataxia‐telangiectasia mutated (ATM) is thought to play
a major role in the caretaking of the overall genome stability, and its mutations have been …

Background. The aim of this study was to evaluate the relations of SDF‐1 and its receptor,
CXCR4, gene variants on oral cancer risk. Methods. PCR‐RFLP was used to measure SDF …