[HTML][HTML] Guts imbalance imbalances the brain: a review of gut microbiota association with neurological and psychiatric disorders

L Mitrea, SA Nemeş, K Szabo, BE Teleky… - Frontiers in …, 2022 - frontiersin.org
In the last ten years, there has been a growing interest regarding the relationship between
gut microbiota, brain, and neurological-associated affections. As multiple preclinical and …

Biological hypotheses, risk factors, and biomarkers of schizophrenia

Z Fišar - Progress in Neuro-Psychopharmacology and …, 2023 - Elsevier
Both the discovery of biomarkers of schizophrenia and the verification of biological
hypotheses of schizophrenia are an essential part of the process of understanding the …

[HTML][HTML] The development and evolution of inhibitory neurons in primate cerebrum

MT Schmitz, K Sandoval, CP Chen, MA Mostajo-Radji… - Nature, 2022 - nature.com
Neuroanatomists have long speculated that expanded primate brains contain an increased
morphological diversity of inhibitory neurons (INs), and recent studies have identified …

The nature of prefrontal cortical GABA neuron alterations in schizophrenia: markedly lower somatostatin and parvalbumin gene expression without missing neurons

SJ Dienel, KN Fish, DA Lewis - American Journal of …, 2023 - Am Psychiatric Assoc
Objective: In schizophrenia, somatostatin (SST) and parvalbumin (PV) mRNA levels are
lower in the dorsolateral prefrontal cortex (DLPFC), but it remains unclear whether these …

[HTML][HTML] Investigating brain aging trajectory deviations in different brain regions of individuals with schizophrenia using multimodal magnetic resonance imaging and …

JD Zhu, YF Wu, SJ Tsai, CP Lin, AC Yang - Translational Psychiatry, 2023 - nature.com
Although many studies on brain-age prediction in patients with schizophrenia have been
reported recently, none has predicted brain age based on different neuroimaging modalities …

[HTML][HTML] Possible neuropathological mechanisms underlying the increased complexity of brain electrical activity in schizophrenia: a computational study

A Khaleghi, MR Mohammadi, K Shahi… - Iranian Journal of …, 2023 - ncbi.nlm.nih.gov
Objective: Schizophrenia is a complex neurodevelopmental illness that is associated with
different deficits in the cerebral cortex and neural networks, resulting in irregularity of brain …

Regional, cellular and species difference of two key neuroinflammatory genes implicated in schizophrenia

CE Murphy, Y Kondo, AK Walker, DA Rothmond… - Brain, Behavior, and …, 2020 - Elsevier
The transcription factor nuclear factor kappa B (NF-κB) regulates the expression of many
inflammatory genes that are overexpressed in a subset of people with schizophrenia …

[HTML][HTML] Detection of advanced brain aging in schizophrenia and its structural underpinning by using normative brain age metrics

CL Chen, TJ Hwang, YH Tung, LY Yang, YC Hsu… - NeuroImage: Clinical, 2022 - Elsevier
Conceptualizing mental disorders as deviations from normative functioning provides a
statistical perspective for understanding the individual heterogeneity underlying psychiatric …

The effect of antipsychotic medications on white matter integrity in first-episode drug-naïve patients with psychosis: a review of DTI studies

R Sagarwala, HA Nasrallah - Asian journal of psychiatry, 2021 - Elsevier
Background Psychotic episodes have been associated with damage to both grey matter
(GM) and white matter (WM). Although a recent meta-analysis suggest that in long term …

Diagnostic specificity and association with cognition of molecular alterations in prefrontal somatostatin neurons in schizophrenia

SJ Dienel, KF Dowling, Z Barile, HH Bazmi… - JAMA …, 2023 - jamanetwork.com
Importance Individuals with schizophrenia (SZ) exhibit pronounced deficits in somatostatin
(SST) messenger RNA (mRNA) levels in the dorsolateral prefrontal cortex (DLPFC) …