Staphylococcus aureus epidemiology, pathophysiology, clinical manifestations and application of nano-therapeutics as a promising approach to combat methicillin …

RHF Bashabsheh, O AL-Fawares… - … and Global Health, 2024 - Taylor & Francis
Staphylococcus aureus is a Gram-positive bacterium and one of the most prevalent
infectious disease-related causes of morbidity and mortality in adults. This pathogen can …

Five major two components systems of Staphylococcus aureus for adaptation in diverse hostile environment

Y Qiu, D Xu, X Xia, K Zhang, RM Aadil, Z Batool… - Microbial …, 2021 - Elsevier
Staphylococcus aureus is an eminent and opportunistic human pathogen that can colonize
in the intestines, skin tissue and perineal regions of the host and cause severe infectious …

[HTML][HTML] In-silico approach to identify novel potent inhibitors against GraR of S. aureus

P Dhankhar, V Dalal, D Golemi-Kotra… - Frontiers in Bioscience …, 2020 - imrpress.com
With rising antibiotic resistance at alarming rates in S. aureus, a major human pathogen, it is
important to identify targets for new antimicrobial therapies. A number of two-component …

Identification of DraRS in Clostridioides difficile, a two-component regulatory system that responds to lipid II-interacting antibiotics

AG Pannullo, BR Zbylicki, CD Ellermeier - Journal of bacteriology, 2023 - Am Soc Microbiol
Clostridioides difficile is a Gram-positive opportunistic pathogen that results in 220,000
infections, 12,000 deaths, and upwards of $1 billion in medical costs in the United States …

HexSDF is required for synthesis of a novel glycolipid that mediates daptomycin and bacitracin resistance in C. difficile

AG Pannullo, Z Guan, H Goldfine, CD Ellermeier - MBio, 2023 - Am Soc Microbiol
Clostridioides difficile is a Gram-positive opportunistic pathogen responsible for 250,000
hospital-associated infections, 12,000 hospital-associated deaths, and $1 billion in medical …

Determinants of maturation of the Staphylococcus aureus autoinducing peptide

L Fang, C Cosgriff, F Alonzo III - Journal of Bacteriology, 2024 - journals.asm.org
The a ccessory g ene r egulatory (Agr) system is required for virulence factor gene
expression and pathogenesis of Staphylococcus aureus. The Agr system is activated in …

A Novel Aza-Derivative Inhibits agr Quorum Sensing Signaling and Synergizes Methicillin-Resistant Staphylococcus aureus to Clindamycin

G Bernabè, M Dal Pra, V Ronca, A Pauletto… - Frontiers in …, 2021 - frontiersin.org
Increasing antibiotic resistance and diminishing pharmaceutical industry investments have
increased the need for molecules that can treat infections caused by dangerous pathogens …

The biofilm proteome of Staphylococcus aureus and its implications for therapeutic interventions to biofilm-associated infections

D Francis, GV Hari, AK Subash, A Bhairaddy… - Advances in protein …, 2024 - Elsevier
Staphylococcus aureus is a major healthcare concern due to its ability to inflict life-
threatening infections and evolve antibiotic resistance at an alarming pace. It is frequently …

Comparative genomic analysis and multilocus sequence typing of Staphylococcus aureus reveals candidate genes for low-temperature tolerance

P Guan, S Fan, W Dong, X Wang, Z Li, M Song… - Science of The Total …, 2024 - Elsevier
Staphylococcus aureus is one of the most frequently detected foodborne pathogens in cold
chain foods. Worryingly, small colony variants (SCVs) can survive in cold environments for a …

Species-Wide Phylogenomics of the Staphylococcus aureus Agr Operon Revealed Convergent Evolution of Frameshift Mutations

V Raghuram, AM Alexander, HQ Loo… - Microbiology …, 2022 - Am Soc Microbiol
Staphylococcus aureus is a prominent nosocomial pathogen that causes several life-
threatening diseases, such as pneumonia and bacteremia. S. aureus modulates the …