Introduction Malaria, a devastating febrile illness caused by protozoan parasites, sickened
247,000,000 people in 2021 and killed 619,000, mostly children and pregnant women in …

Malaria is a global infectious disease that remains a leading cause of morbidity and mortality
in the developing world. Multiple environmental and host and parasite factors govern the …

Malaria, caused by Plasmodium parasites, remains one of the most devastating infectious
diseases worldwide, despite control efforts to lower morbidity and mortality. Both advanced …

Extracellular vesicles (EVs) are cell-derived nanoparticles that can be used as novel
biomaterials. In the development of EVs-based therapeutic systems, it is essential to …

Radiation-attenuated sporozoite (RAS) vaccines can completely prevent blood stage
Plasmodium infection by inducing liver-resident memory CD8+ T cells to target parasites in …

Abstract Development of next-generation vaccines against Plasmodium falciparum (Pf) is a
priority. Many malaria vaccines target the pre-erythrocytic sporozoite (SPZ) and liver stages …

Simple Summary Cell-based oncotherapies are gaining considerable terrain in the last
years thanks to the development of safe and promising treatments against cancer. A better …

Liver stage (LS) Plasmodia mature in 2–2.5 days in rodents compared to 5–6 days in
humans. Plasmodium-specific CD8+ T cell expansion differs across these varied timespans …

We previously reported a protective antibody response in mice immunized with synthetic
microparticle vaccines made using layer-by-layer fabrication (LbL-MP) and containing the …

7DW8-5 is a potent glycolipid adjuvant that improves malaria vaccine efficacy in mice by
inducing IFN-γ and increasing protective CD8+ T cell responses. The addition of 7DW8-5 …