Serum osmolality and hyperosmolar states

B Büyükkaragöz, SA Bakkaloğlu - Pediatric Nephrology, 2023 - Springer
Serum osmolality is the sum of the osmolalities of every single dissolved particle in the blood
such as sodium and associated anions, potassium, glucose, and urea. Under normal …

Challenges in the diagnosis of ethylene glycol poisoning

DJ McQuade, PI Dargan… - Annals of clinical …, 2014 - journals.sagepub.com
Ethylene glycol poisoning, while uncommon, is clinically significant due to the associated
risk of severe morbidity or lethality and it continues to occur in many countries around the …

A retrospective analysis of glycol and toxic alcohol ingestion: utility of anion and osmolal gaps

MD Krasowski, RM Wilcoxon, J Miron - BMC clinical pathology, 2012 - Springer
Background Patients ingesting ethylene glycol, isopropanol, methanol, and propylene glycol
('toxic alcohols') often present with non-specific signs and symptoms. Definitive diagnosis of …

A rapid analysis of plasma/serum ethylene and propylene glycol by headspace gas chromatography

A Ehlers, C Morris, MD Krasowski - Springerplus, 2013 - Springer
A rapid headspace-gas chromatography (HS-GC) method was developed for the analysis of
ethylene glycol and propylene glycol in plasma and serum specimens using 1, 3 …

Activation of nuclear factor of activated T cells 5 in the peritoneal membrane of uremic patients

D Kitterer, J Latus, C Ulmer, P Fritz… - American Journal …, 2015 - journals.physiology.org
Peritoneal inflammation and fibrosis are responses to the uremic milieu and exposure to
hyperosmolar dialysis fluids in patients on peritoneal dialysis. Cells respond to high …

Formulas for calculated osmolarity and osmolal gap: a study of diagnostic accuracy

F Lepeytre, M Ghannoum, H Ammann, F Madore… - American Journal of …, 2017 - Elsevier
Background The osmolal gap has been used for decades to screen for exposure to toxic
alcohols. However, several issues may affect its reliability. We aimed to develop equations …

Changes in osmol gap in chronic kidney disease: an exploratory study

G Shaikh, R Sehgal, S Sandhu, S Vaddineni… - Renal …, 2014 - Taylor & Francis
Aim: There is no data on osmol gap (OG) in chronic kidney disease (CKD) by stage and
limited data on OG in adults on maintenance hemodialysis (HD). We aimed to examine the …

The potential role of NFAT5 and osmolarity in peritoneal injury

H Seeger, D Kitterer, J Latus… - BioMed research …, 2015 - Wiley Online Library
A rise in osmotic concentration (osmolarity) activates the transcription factor Nuclear Factor
of Activated T Cells 5 (NFAT5, also known as Tonicity‐responsive Enhancer Binding Protein …

Osmolal gap in hemodialyzed uremic patients

I Griveas, A Gompou, I Kyritsis… - Artificial …, 2012 - Wiley Online Library
Osmolality is an expression of the number of particles in a given weight of solvent (mOsm).
Measured osmolality is determined by the osmometer, and calculated osmolality is …

Quiz Page June 2011: Profound Metabolic Acidosis and Abdominal Pain in a Diabetic Patient on Long-term Hemodialysis

C Parke, YHH Lien - American Journal of Kidney Diseases, 2011 - ajkd.org
A 62-year-old white man presented to the emergency department with profound abdominal
pain. He had end-stage renal disease (ESRD) secondary to diabetic nephropathy and had …