Interactions between fullerene derivatives and biological systems

MJ Siringan, A Dawar, J Zhang - Materials Chemistry Frontiers, 2023 - pubs.rsc.org
Attention towards nanoparticles from the pharmaceutical and biomedical fields has
significantly increased due to their attractive surface modification, high drug-loading, and …

Heavy Atom-Free Triplet Photosensitizers: Molecular Structure Design, Photophysical Properties and Application in Photodynamic Therapy

X Xiao, X Zhao, X Chen, J Zhao - Molecules, 2023 - mdpi.com
Photodynamic therapy (PDT) is a promising method for the treatment of cancer, because of
its advantages including a low toxicity, non-drug-resistant character, and targeting capability …

Highly aqueously stable C60‐polymer nanoparticles with excellent photodynamic property for potential cancer treatment

D Wang, J Zhao, RJ Mulder, J Ratcliffe, C Wang… - Smart …, 2023 - Wiley Online Library
Fullerenes are a class of carbon nanomaterials that find a wide range of applications in
biomedical fields, especially for photodynamic cancer therapy because of its photosensitive …

Enhanced Uptake and Phototoxicity of C60@albumin Hybrids by Folate Bioconjugation

A Cantelli, M Malferrari, EJ Mattioli, A Marconi, G Mirra… - Nanomaterials, 2022 - mdpi.com
Fullerenes are considered excellent photosensitizers, being highly suitable for
photodynamic therapy (PDT). A lack of water solubility and low biocompatibility are, in many …

Porphyrin as photosensitizers for controlling marine biodegradation of polymer composites

S Hino, A Masui, H Okamura, N Kawasaki… - …, 2024 - ACS Publications
Biodegradable polymer–photosensitizer composites were developed, which is suppressed
biodegradation due to bactericidal activity under light irradiation but proceeds under dark …

“On‐Off” Switching of Functional Guest Molecules via Exchange of Natural Product Solubilizing Agents

R Kawasaki, A Ikeda - ChemBioChem, 2023 - Wiley Online Library
For the development of delivery systems, the solubilization of hydrophobic guest molecules
in water is an important yet challenging task. This can be achieved by preparing stable …

HER‐2‐Targeted Boron Neutron Capture Therapy with Carborane‐integrated Immunoliposomes Prepared via an Exchanging Reaction

R Kawasaki, A Oshige, K Yamana… - … A European Journal, 2023 - Wiley Online Library
Boron neutron capture therapy (BNCT) is a promising modality for cancer treatment because
of its minimal invasiveness. To maximize the therapeutic benefits of BNCT, the development …

Putting a “C60 Ball” and Chain to Chlorin e6 Improves Its Cellular Uptake and Photodynamic Performances

M Di Sante, A Kaltenbrunner, M Lombardo, A Danielli… - Pharmaceuticals, 2023 - mdpi.com
Chlorin e6 (Ce6) and fullerene (C60) are among the most used photosensitizers (PSs) for
photodynamic therapy (PDT). Through the combination of the chemical and photophysical …

Guanidinium-appended γ-cyclodextrin: efficient fullerene solubiliser for enhanced photodynamic therapy

MHK Man, HCM Yau, K Okuro - Materials Chemistry Frontiers, 2025 - pubs.rsc.org
Efficient solubilisation of fullerenes in aqueous media is crucial for their photodynamic
therapy (PDT) applications. We demonstrated the efficacy of guanidinium-appended γ …

Extracellular vesicles containing fullerene derivatives prepared by an exchange reaction for photodynamic therapy

N Kono, R Kawasaki, A Oshige, K Nishimura… - Journal of Materials …, 2024 - pubs.rsc.org
Extracellular vesicles (EVs) have excellent biocompatibility and long retention times in the
circulation and have consequently been expected to be useful as drug-delivery systems …