Malaria, caused by the protozoan parasites of the genus Plasmodium, is a major health
problem in many countries of the world. Five parasite species namely, Plasmodium …

Plasmodium vivax is the most geographically widespread cause of human malaria and is
responsible for the majority of cases outside of the African continent. While great progress …

Background Treatment failure of chloroquine for P. vivax infections has reached high levels
in the eastern provinces of Indonesia, however, in vitro characterization of chloroquine …

Emerging antimalarial drug resistance may undermine current efforts to control and
eliminate Plasmodium vivax, the most geographically widespread yet neglected human …

Expanding drug resistance could become a major problem in malaria treatment, as only a
limited number of effective antimalarials are available. Drug resistance has been associated …

Abstract Background Increased resistance by Plasmodium falciparum parasites led to the
withdrawal of the antimalarial drugs chloroquine and sulphadoxine-pyrimethamine in …

This review article aims to investigate the genotypic profiles of Plasmodium falciparum and
Plasmodium vivax isolates collected across a wide geographic region and their association …

Abstract The Asia–Pacific region faces formidable challenges in achieving malaria
elimination by the proposed target in 2030. Molecular surveillance of Plasmodium parasites …

No data were available concerning Plasmodium vivax resistance to chloroquine (CQ) in
Madagascar. We investigated the therapeutic efficacy of CQ in P. vivax malaria, the …

The global emergence of Plasmodium vivax strains resistant to chloroquine (CQ) since the
late 1980s is complicating the current international efforts for malaria control and elimination …