Annual Research Review: Puberty and the development of anhedonia–considering childhood adversity and inflammation

T Gupta, KL Eckstrand… - Journal of Child …, 2024 - Wiley Online Library
Anhedonia, or diminished pleasure and motivation, is a symptom of severe mental illness
(eg, depressive disorder, bipolar disorder, schizophrenia) that emerges during adolescence …

[HTML][HTML] Cannabis, endocannabinoids and brain development: From embryogenesis to adolescence

RJ Rodrigues, JM Marques, A Köfalvi - Cells, 2024 - mdpi.com
The endocannabinoid signalling system (ECS) plays a critical role from the very beginning
of embryogenesis. Accordingly, the ECS is engaged early on in nervous system …

Balance of activity during a critical period tunes a developing network

I Hunter, B Coulson, T Pettini, JJ Davies, J Parkin… - Elife, 2024 - elifesciences.org
Developing neural circuits are influenced by activity and are especially sensitive to changes
in activity during critical periods (CPs) of development. Changes occurring during a CP often …

Outcomes of early social experiences on glucocorticoid and endocannabinoid systems in the prefrontal cortex of male and female adolescent rats

L Rullo, LM Losapio, C Morosini, F Mottarlini… - Frontiers in Cellular …, 2023 - frontiersin.org
Social and emotional experiences differently shape individual's neurodevelopment inducing
substantial changes in neurobiological substrates and behavior, particularly when they …

[HTML][HTML] Dynamic Insights into Dopamine Axon Growth in Adolescence and its Implications for Psychiatric Risk

RG Avramescu, T Capolicchio, C Flores - Current Opinion in Behavioral …, 2024 - Elsevier
Adolescence and the development of the dopaminergic system have long been shown to be
inextricably linked. Common adolescent experiences, such as substance exposure and …

The effects of Peripubertal THC exposure in neurodevelopmental rat models of psychopathology

M Di Bartolomeo, T Stark, S Di Martino… - International Journal of …, 2023 - mdpi.com
Adolescent exposure to cannabinoids as a postnatal environmental insult may increase the
risk of psychosis in subjects exposed to perinatal insult, as suggested by the two-hit …

Adolescent neurodevelopment within the context of impulsivity and substance use

RJ Green, LR Meredith, L Mewton… - Current addiction reports, 2023 - Springer
Abstract Purpose of Review The aim of the present review is to provide an update on recent
studies examining adolescent neurodevelopment in the context of impulsivity and substance …

Psychological resilience interventions for adolescents during the COVID-19 pandemic

J Xing, X Xu, X Li, Q Luo - Behavioral Sciences, 2023 - mdpi.com
The COVID-19 pandemic has had severe mental health effects on adolescents.
Psychological resilience is the ability to recover quickly from adversity and can help …

[HTML][HTML] The connecting brain in context: How adolescent plasticity supports learning and development

AE Baker, A Galván, AJ Fuligni - Developmental Cognitive Neuroscience, 2025 - Elsevier
Puberty initiates significant neurobiological changes that amplify adolescents'
responsiveness to their environment, facilitating neural adaptation through processes like …

Targeting the endocannabinoidome in neurodegenerative disorders

H Ishiguro - Frontiers in Aging Neuroscience, 2023 - frontiersin.org
Current studies have unveiled the important roles of the endocannabinoid system (ECS) in
multiple aspects of neural functions, including motor coordination, learning and memory …