Locoregional therapies in the era of molecular and immune treatments for hepatocellular carcinoma

JM Llovet, T De Baere, L Kulik, PK Haber… - Nature reviews …, 2021 - nature.com
Hepatocellular carcinoma (HCC) is the fourth leading cause of cancer-related mortality and
has an increasing incidence worldwide. Locoregional therapies, defined as imaging-guided …

Lipid based nanoparticles as a novel treatment modality for hepatocellular carcinoma: a comprehensive review on targeting and recent advances

K Mahmoud, S Swidan, M El-Nabarawi… - Journal of …, 2022 - Springer
Liver cancer is considered one of the deadliest diseases with one of the highest disease
burdens worldwide. Among the different types of liver cancer, hepatocellular carcinoma is …

Hypoxia blocks ferroptosis of hepatocellular carcinoma via suppression of METTL14 triggered YTHDF2‐dependent silencing of SLC7A11

Z Fan, G Yang, W Zhang, Q Liu, G Liu… - Journal of cellular …, 2021 - Wiley Online Library
Residue hepatocellular carcinoma (HCC) cells enduring hypoxic environment triggered by
interventional embolization obtain more malignant potential with little clarified mechanism …

Recent advancements of nanomedicine towards antiangiogenic therapy in cancer

A Mukherjee, VS Madamsetty, MK Paul… - International Journal of …, 2020 - mdpi.com
Angiogenesis is a process of generation of de-novo blood vessels from already existing
vasculature. It has a crucial role in different physiological process including wound healing …

A highly selective and potent CXCR4 antagonist for hepatocellular carcinoma treatment

JS Song, CC Chang, CH Wu, TK Dinh… - Proceedings of the …, 2021 - National Acad Sciences
The CXC chemokine receptor type 4 (CXCR4) receptor and its ligand, CXCL12, are
overexpressed in various cancers and mediate tumor progression and hypoxia-mediated …

HIF-2α-targeted interventional chemoembolization multifunctional microspheres for effective elimination of hepatocellular carcinoma

M Chen, G Shu, X Lv, X Xu, C Lu, E Qiao, S Fang… - Biomaterials, 2022 - Elsevier
Transcatheter arterial chemoembolization (TACE) is widely used for the treatment of
advanced hepatocellular carcinoma (HCC). However, the long-term hypoxic …

Autophagy-targeted calcium phosphate nanoparticles enable transarterial chemoembolization for enhanced cancer therapy

G Yuan, Y Xu, X Bai, W Wang, X Wu… - … Applied Materials & …, 2023 - ACS Publications
Transarterial chemoembolization (TACE) is commonly used for treating advanced
hepatocellular carcinoma (HCC). However, the instability of lipiodol-drug emulsion and the …

Recent Progress in Advanced Hydrogel‐Based Embolic Agents: From Rational Design Strategies to Improved Endovascular Embolization

X Li, MW Ullah, B Li, H Chen - Advanced Healthcare Materials, 2023 - Wiley Online Library
Transcatheter arterial embolization, a minimally invasive treatment to deliberately occlude
the blood vessels, has become a safe and effective procedure for the management of …

[HTML][HTML] Immunotherapy for targeting cancer stem cells in hepatocellular carcinoma

X Dai, Y Guo, Y Hu, X Bao, X Zhu, Q Fu, H Zhang… - Theranostics, 2021 - ncbi.nlm.nih.gov
The rapid development and remarkable success of checkpoint inhibitors have provided
significant breakthroughs in cancer treatment, including hepatocellular carcinoma (HCC) …

Transarterial chemoembolization plus a PD‐1 inhibitor with or without lenvatinib for intermediate‐stage hepatocellular carcinoma

YJ Xiang, K Wang, HM Yu, XW Li… - Hepatology …, 2022 - Wiley Online Library
Aim Transarterial chemoembolization (TACE) combined with a PD‐1 inhibitor and TACE
combined with a PD‐1 inhibitor and lenvatinib have recently been reported as promising …