In vivo near-infrared (NIR) fluorescence imaging is an emerging biomedical imaging
modality for use in both fundamental scientific research and clinical practice. Owing to …

Fibrillar aggregates of the amyloid-β protein (Aβ) are the main component of the senile
plaques found in brains of patients with Alzheimer's disease (AD). Development of probes …

Fluorescence imaging in the second near‐infrared (NIR‐II) window holds great promise for
in vivo visualization of amyloid‐β (Aβ) pathology, which can facilitate characterization and …

Self-assembled peptide and protein amyloid nanostructures have traditionally been
considered only as pathological aggregates implicated in human neurodegenerative …

High-fidelity mapping of amyloid-β (Aβ) plaques is critical for the early detection of
Alzheimer's disease. However, in vivo probing of Aβ plaques by commercially available …

Neurodegenerative diseases are debilitating disorders that feature progressive and
selective loss of function or structure of anatomically or physiologically associated neuronal …

Fluorophores and probes are invaluable for the visualization of the location and dynamics of
gene expression, protein expression, and molecular interactions in complex living systems …

Amyloids are a broad class of proteins and peptides that can misfold and assemble into long
unbranched fibrils with a cross-β conformation. These misfolding and aggregation events …

Deposits of amyloid-β (Aβ) in the brains of rodents can be analysed by invasive intravital
microscopy on a submillimetre scale, or via whole-brain images from modalities lacking the …

Protein misfolding and aggregation, a key contributor to the progression of numerous
neurodegenerative diseases, results in functional deficiencies and the creation of harmful …