As the first-line antimalarial drugs, artemisinins gained wide acceptance after the
emergence of resistance to chloroquine in the 1950s. Artemisinin-based drugs have saved …

The field of Traditional Chinese Medicine (TCM) represents a vast and largely untapped
resource for modern medicine. Exemplified by the success of the antimalarial artemisinin …

Artemisinin and its derivatives (collectively termed as artemisinins) are among the most
important and effective antimalarial drugs, with proven safety and efficacy in clinical use …

Artemisinin and its derivatives represent the most important and influential class of drugs in
the fight against malaria. Since the discovery of artemisinin in the early 1970s, the global …

Emergence and spread of resistance in Plasmodium falciparum to the frontline treatment
artemisinin-based combination therapies (ACTs) in the epicenter of multidrug resistance of …

Malaria has been a global epidemic health threat since ancient times. It still claims roughly
half a million lives every year in this century. Artemisinin and its derivatives, are frontline …

Artemisinin combination therapies (ACTs) have been used as the first‐line treatments
against Plasmodium falciparum malaria for decades. Recent advances in chemical …

Activity-based probes (ABPs) are widely used to monitor the activity of enzyme families in
biological systems. Inferring enzyme activity from probe reactivity requires that the probe …

Protein S-palmitoylation is a post-translational modification that plays a crucial role in cancer
cells by regulating the function and localization of oncoproteins and tumor suppressor …

Protein lipidation dynamically controls protein localization and function within cellular
membranes. A unique form of protein O-fatty acylation in Corynebacterium, termed protein O …