Sodium–glucose co‐transporter 2 inhibitors as an early, first‐line therapy in patients with heart failure and reduced ejection fraction

D Tomasoni, GC Fonarow, M Adamo… - European journal of …, 2022 - Wiley Online Library
Sodium–glucose co‐transporter 2 (SGLT2) inhibitors have recently been recommended as a
foundational therapy for patients with heart failure (HF) and reduced ejection fraction …

Heart failure: an update from the last years and a look at the near future

M Riccardi, AM Sammartino, M Piepoli… - ESC heart …, 2022 - Wiley Online Library
In the last years, major progress occurred in heart failure (HF) management. Quadruple
therapy is now mandatory for all the patients with HF with reduced ejection fraction. Whilst …

2023 ACC expert consensus decision pathway on management of heart failure with preserved ejection fraction: a report of the American College of Cardiology …

MM Kittleson, GS Panjrath, K Amancherla… - Journal of the American …, 2023 - jacc.org
The American College of Cardiology (ACC) has a long history of developing documents (eg,
decision pathways, health policy statements, appropriate use criteria) to provide members …

Worsening of chronic heart failure: definition, epidemiology, management and prevention. A clinical consensus statement by the Heart Failure Association of the …

M Metra, D Tomasoni, M Adamo… - European Journal of …, 2023 - Wiley Online Library
Episodes of worsening symptoms and signs characterize the clinical course of patients with
chronic heart failure (HF). These events are associated with poorer quality of life, increased …

Effects of Dapagliflozin in Chronic Kidney Disease, With and Without Other Cardiovascular Medications: DAPA‐CKD Trial

GM Chertow, R Correa‐Rotter, P Vart… - Journal of the …, 2023 - Am Heart Assoc
Background The DAPA‐CKD (Dapagliflozin and Prevention of Adverse Outcomes in
Chronic Kidney Disease) trial (NCT03036150) demonstrated that dapagliflozin reduced the …

Empagliflozin and left ventricular remodeling in people without diabetes: primary results of the EMPA-HEART 2 CardioLink-7 randomized clinical trial

KA Connelly, CD Mazer, P Puar, H Teoh, CH Wang… - Circulation, 2023 - Am Heart Assoc
Background: Sodium-glucose cotransporter 2 inhibitors have been demonstrated to promote
reverse cardiac remodeling in people with diabetes or heart failure. Although it has been …

Efficacy of dapagliflozin according to geographic location of patients with heart failure

T Kondo, X Wang, M Yang, PS Jhund… - Journal of the American …, 2023 - jacc.org
Background Because clinical characteristics and prognosis vary by geographic region in
patients with heart failure (HF), the response to treatment may also vary. A previous report …

Empagliflozin: a review in symptomatic chronic heart failure

JE Frampton - Drugs, 2022 - Springer
Empagliflozin (Jardiance®), a sodium-glucose cotransporter 2 inhibitor (SGLT2i) initially
developed to treat type 2 diabetes mellitus (T2DM), has also been approved in the EU and …

Dapagliflozin reduces pulmonary vascular damage and susceptibility to atrial fibrillation in right heart disease

C Dai, B Kong, W Shuai, Z Xiao, T Qin, J Fang… - ESC Heart …, 2023 - Wiley Online Library
Aims Sodium‐glucose cotransporter 2 inhibitors (SGLT2is) have made considerable
progress in the field of heart failure, but their application in arrhythmia remains to be in …

β-blockers are not all the same: pharmacologic similarities and differences, potential combinations and clinical implications

S Taddei, N Tsabedze, RS Tan - Current Medical Research and …, 2024 - Taylor & Francis
Abstract β-blockers are a heterogeneous class, with individual agents distinguished by
selectivity for β1-vs. β2-and α-adrenoceptors, presence or absence of partial agonist activity …