HCC comprises∼ 80% of primary liver cancer. HCC is the only major cancer for which death
rates have not improved over the last 10 years. Most patients are diagnosed with advanced …

Liver cancer is the second most common cause of cancer-related death. The major forms of
primary liver cancer are hepatocellular carcinoma (HCC) and intrahepatic …

Recent evidence suggests that hepatocellular carcinoma (HCC) is organized by a subset of
cells with stem cell features (cancer stem cells; CSCs). CSCs are considered a pivotal target …

Abstract THY1 (CD90) is a 25–37-kDa heavily N-glycosylated, glycophosphatidylinositol
(GPI) anchored cell surface protein. It is usually expressed on thymocytes, mesenchymal …

Alpha fetoprotein (AFP) is the most widely used diagnostic and prognostic serum biomarker
for hepatocellular carcinoma (HCC). Despite its wide clinical use, a systematic …

Although the CD90 (Thy-1) was proposed as biomarker of several tumors and cancer stem
cells, the involvement of this molecule in the progression of hepatocellular carcinoma (HCC) …

Background & aims Among the multiplicity of factors involved in rising incidence of
hepatocellular carcinoma (HCC)-the second deadliest cancer, late diagnosis of early-stage …

Cancer stem cells (CSCs) play a central role in tumor progression, recurrence, and
resistance to conventional therapies, making them a critical focus in oncology research. This …

CD44 and miR-221 are upregulated in hepatocellular carcinoma (HCC) cell lines and
tumors, however a connection between the two has not been identified. As the expression of …

Background: Proteoglycans are involved in neoangiogenesis and transduction of oncogenic
signals, two hallmarks of carcinogenesis. Methods: This study sought to assess the …