Cilia structure and intraflagellar transport differentially regulate sensory response dynamics within and between C. elegans chemosensory neurons

A Philbrook, MP O'Donnell, L Grunenkovaite… - PLoS …, 2024 - journals.plos.org
Sensory neurons contain morphologically diverse primary cilia that are built by intraflagellar
transport (IFT) and house sensory signaling molecules. Since both ciliary structural and …

Worm-Based Diagnosis Combining Microfluidics toward Early Cancer Screening

Y Shi, C Cui, S Chen, S Chen, Y Wang, Q Xu, L Yang… - Micromachines, 2024 - mdpi.com
Early cancer diagnosis increases therapy efficiency and saves huge medical costs.
Traditional blood-based cancer markers and endoscopy procedures demonstrate limited …

A neurotransmitter atlas of C. elegans males and hermaphrodites

C Wang, B Vidal, S Sural, C Loer, GR Aguilar… - Elife, 2024 - elifesciences.org
Mapping neurotransmitter identities to neurons is key to understanding information flow in a
nervous system. It also provides valuable entry points for studying the development and …

Insights and progress on the biosynthesis, metabolism, and physiological functions of gamma-aminobutyric acid (GABA): a review

Q Zhang, L Zhu, H Li, Q Chen, N Li, J Li, Z Zhao, D Xiao… - PeerJ, 2024 - peerj.com
GABA (γ-aminobutyric acid) is a non-protein amino acid that occurs naturally in the human
brain, animals, plants and microorganisms. It is primarily produced by the irreversible action …

From value to saliency: Neural computations of subjective value under uncertainty in PTSD

R Jia, L Ruderman, C Gordon, D Ehrlich, M Horvath… - bioRxiv, 2020 - biorxiv.org
Military personnel engaged in combat are vulnerable to Posttraumatic Stress Disorder
(PTSD), following traumatic experiences in the battlefield. Prior research has mostly …

Astrocytic Bestrophin1 in the Anterior Cingulate Cortex Modulates the Formation and Persistence of Morphine Addiction Memory

L Sun, Z Liu, Y Li, X Lin, Y Huo, S Guo, X Fan, X Ye… - 2024 - researchsquare.com
Emerging evidence indicates that astrocytes play a vital role in both the establishment and
preservation of memories. However, their specific contribution to addiction-related memory …