Nitric oxide (NO) is a pleiotropic molecule critical to a number of physiological and
pathological processes. The last decade has witnessed major advances in dissecting NO …

As a free radical and endogenous effector molecule, mammalian endogenous nitric oxide
(NO) is mainly derived from nitric oxide synthase (NOS) via L-arginine. NO participates in …

Significance: Gastrointestinal (GI) cancer taken together constitutes one of the most common
cancers worldwide with a broad range of etiological mechanisms. In this review, we have …

Objects. The aim of this study is to evaluate protein oxidation, DNA damage, and lipid
peroxidation in patients with gastric cancer and to investigate the relationship between …

The gastrointestinal epithelium functions as physical and innate immune barriers against
commensal or pathogenic microbes. NADPH oxidase 1 (Nox1) and dual oxidase 2 (Duox2) …

Helicobacter pylori infection is the most important acquired risk factor for gastric cancer. The
infection initiates a chronic inflammatory process that eventually alters the physiology of the …

Although degenerative diseases of the central nervous system, including Alzheimer's
disease (AD), have an increasingly high impact on aged population their association with …

Abstract Background and Objective Chronic gastritis frequently progresses into
precancerous intestinal metaplasia and intraepithelial neoplasia lesions. Rebamipide is a …

Gastric adenocarcinoma not located in the cardia still remains second only to lung cancer as
the leading cause of cancer-related mortality worldwide, whereas adenocarcinoma of the …

Gastric cancer is considered one of the most common causes of cancer-related death
worldwide and, thus, a major health problem. A variety of environmental factors including …