[HTML][HTML] Ten approaches that improve immunostaining: a review of the latest advances for the optimization of immunofluorescence

R Piña, AI Santos-Díaz, E Orta-Salazar… - International journal of …, 2022 - mdpi.com
Immunostaining has emerged as one of the most common and valuable techniques that
allow the localization of proteins at a quantitative level within cells and tissues using …

[HTML][HTML] Identification of blood vascular endothelial stem cells by the expression of protein C receptor

QC Yu, W Song, D Wang, YA Zeng - Cell research, 2016 - nature.com
Vascular growth and remodeling are dependent on the generation of new endothelial cells
from stem cells and the involvement of perivascular cells to maintain vessel integrity and …

MMP9‐Responsive Graphene Oxide Quantum Dot‐Based Nano‐in‐Micro Drug Delivery System for Combinatorial Therapy of Choroidal Neovascularization

K Huang, X Liu, Z Lv, D Zhang, Y Zhou, Z Lin, J Guo - Small, 2023 - Wiley Online Library
Age‐related macular degeneration (AMD), especially wet AMD with choroidal
neovascularization (CNV), commonly causes blindness in older patients and disruption of …

[HTML][HTML] A mouse model for laser-induced choroidal neovascularization

RS Shah, BT Soetikno, M Lajko… - Journal of visualized …, 2015 - ncbi.nlm.nih.gov
The mouse laser-induced choroidal neovascularization (CNV) model has been a crucial
mainstay model for neovascular age-related macular degeneration (AMD) research. By …

[HTML][HTML] Fabrication and evaluation of gellan gum/hyaluronic acid hydrogel for retinal tissue engineering biomaterial and the influence of substrate stress relaxation on …

J Youn, JH Choi, S Lee, W Lee, SW Lee, W Kim… - Molecules, 2022 - mdpi.com
Cell therapies for age-related macular degeneration (AMD) treatment have been developed
by integrating hydrogel-based biomaterials. Until now, cell activity has been observed only …

[HTML][HTML] N-palmitoyl-D-glucosamine, a natural monosaccharide-based glycolipid, inhibits TLR4 and prevents LPS-induced inflammation and neuropathic pain in mice

M Iannotta, C Belardo, MC Trotta, FA Iannotti… - International Journal of …, 2021 - mdpi.com
Toll-like receptors (TLRs) are key receptors through which infectious and non-infectious
challenges act with consequent activation of the inflammatory cascade that plays a critical …

Quantitative mapping of keratin networks in 3D

R Windoffer, N Schwarz, S Yoon, T Piskova… - Elife, 2022 - elifesciences.org
Mechanobiology requires precise quantitative information on processes taking place in
specific 3D microenvironments. Connecting the abundance of microscopical, molecular …

[HTML][HTML] Prolactin protects retinal pigment epithelium by inhibiting sirtuin 2-dependent cell death

RM García, DA Zamarripa, E Arnold, X Ruiz-Herrera… - …, 2016 - thelancet.com
The identification of pathways necessary for retinal pigment epithelium (RPE) function is
fundamental to uncover therapies for blindness. Prolactin (PRL) receptors are expressed in …

[HTML][HTML] Overexpression of CERKL protects retinal pigment epithelium mitochondria from oxidative stress effects

R García-Arroyo, A Gavaldà-Navarro, F Villarroya… - Antioxidants, 2021 - mdpi.com
The precise function of CERKL, a Retinitis Pigmentosa (RP) causative gene, is not yet fully
understood. There is evidence that CERKL is involved in the regulation of autophagy, stress …

[HTML][HTML] Loss of the heterogeneous expression of flippase ATP11B leads to cerebral small vessel disease in a normotensive rat model

S Quick, TV Procter, J Moss, L Seeker, M Walton… - Acta …, 2022 - Springer
Cerebral small vessel disease (SVD) is the leading cause of vascular dementia, causes a
quarter of strokes, and worsens stroke outcomes. The disease is characterised by patchy …