Chemokines are a family of small, highly conserved cytokines that mediate various
biological processes, including chemotaxis, hematopoiesis, and angiogenesis, and that …

This review focuses on the construction and application of structural chemokine receptor
models for the elucidation of molecular determinants of chemokine receptor modulation and …

Chemokines drive cell migration through their interactions with seven-transmembrane (7TM)
chemokine receptors on cell surfaces. The atypical chemokine receptor 3 (ACKR3) binds …

Many biological functions of peptides are mediated through G protein-coupled receptors
(GPCRs). Upon ligand binding, GPCRs undergo conformational changes that facilitate the …

Disulfide Bonds in Protein Folding and Stability | Oxidative Folding of Proteins: Basic
Principles, Cellular Regulation and Engineering | Books Gateway | Royal Society of Chemistry …

Chemokines and their receptors are orchestrators of cell migration in humans. Because
dysregulation of the receptor-chemokine system leads to inflammation and cancer, both …

Highlights•Chemokine interactions with receptors trigger cell migration in immunity and
cancer.•2015 brought high-resolution insights into the structural basis of these …

Chemokines are a family of signaling proteins that play a crucial role in cell–cell
communication, cell migration, and cell trafficking, particularly leukocytes, under both normal …

Chemokines are small soluble proteins that drive cell migration through the formation of
concentration gradients. Chemokine binding to G protein-coupled chemokine receptors in …

Arrestins (arr) are multifunctional cytosolic adaptors that bind to active and phosphorylated G
protein‐coupled receptors (GPCRs) via a highly versatile interface. Arrestins stop G protein …