QbD approach empowers the pharma researchers to minimize the number of experimental
trials and time. It helps identify the significant, influential factors such as critical material …

Polymeric nanoparticles prepared using high pressure homogenizer (HPH) present some
unique challenges during manufacturing which can be better understood by application of …

Gefitinib (GFT) is an anticancer drug which shows poor aqueous solubility and
bioavailability. The quantitative solubility data of GFT in any aqueous, organic or the mixture …

Background Diabetic foot ulcer is an intractable complication of diabetes, characterized by
the disturbed inflammatory and proliferative phases of wound healing. Sesamol, a phenolic …

Purpose The present study aimed to develop gefitinib-loaded solid lipid nanoparticles (GEF-
SLN), and GEF-loaded PEGylated SLN (GEF-P-SLN) for targeting metastatic lung cancer …

In the present study, gefitinib loaded cellulose acetate butyrate nanoparticles (Gnb-NPs)
were prepared and then incorporated into thermo-sensitive chitosan/β-glycerophosphate …

Gefitinib as an epidermal growth factor receptor tyrosine kinase inhibitor has strong potential
in lung cancer therapy. However, a major challenge of using gefitinib is its toxicities. In the …

Gefitinib (GEF) is utilized in clinical settings for the treatment of metastatic lung cancer.
However, premature drug release from nanoparticles in vivo increases the exposure of …

Cancer is one of the leading causes of death with a mortality rate of 12%. Although
significant progress has been achieved in cancer research, the effective treatment of cancer …

Over the last few decades, there has been an impressive progress on developing novel drug
delivery systems and targeted therapies through the use of Nanotechnology. In particular …