The role of cancer stem cell markers in ovarian cancer
K Frąszczak, B Barczyński - Cancers, 2023 - mdpi.com
Simple Summary This manuscript focuses on cancer stem cells and the diagnostic potential
of selected biomarkers of these cells in ovarian cancers. Ovarian cancer has nonspecific …
of selected biomarkers of these cells in ovarian cancers. Ovarian cancer has nonspecific …
Desmoplastic small round cell tumor cancer stem cell-like cells resist chemotherapy but remain dependent on the EWSR1-WT1 oncoprotein
JW Magrath, HJ Kang, A Hartono… - Frontiers in Cell and …, 2022 - frontiersin.org
Desmoplastic Small Round Cell Tumor (DSRCT) is a rare and aggressive pediatric cancer
driven by the EWSR1-WT1 fusion oncogene. Combinations of chemotherapy, radiation and …
driven by the EWSR1-WT1 fusion oncogene. Combinations of chemotherapy, radiation and …
MK2 promotes Tfcp2l1 degradation via β-TrCP ubiquitin ligase to regulate mouse embryonic stem cell self-renewal
Y Zhang, H Ding, X Wang, X Wang, S Wan, A Xu… - Cell Reports, 2021 - cell.com
Tfcp2l1 can maintain mouse embryonic stem cell (mESC) self-renewal. However, it remains
unknown how Tfcp2l1 protein stability is regulated. Here, we demonstrate that β-transducin …
unknown how Tfcp2l1 protein stability is regulated. Here, we demonstrate that β-transducin …
Micelle-like clusters in phase-separated Nanog condensates: A molecular simulation study
The phase separation model for transcription suggests that transcription factors (TFs),
coactivators, and RNA polymerases form biomolecular condensates around active gene loci …
coactivators, and RNA polymerases form biomolecular condensates around active gene loci …
Sa12b improves biological activity of human degenerative nucleus pulposus mesenchymal stem cells in a severe acid environment by inhibiting acid-sensitive ion …
Z Wang, L Han, H Chen, S Zhang, S Zhang… - … in Bioengineering and …, 2022 - frontiersin.org
Sa12b is a wasp peptide that can inhibit acid-sensitive ion channels (ASICs). The biological
effects of nucleus pulposus mesenchymal stem cells (NP-MSCs) have not been …
effects of nucleus pulposus mesenchymal stem cells (NP-MSCs) have not been …
ESRRB facilitates the conversion of trophoblast-like stem cells from induced pluripotent stem cells by directly regulating CDX2
S Yu, R Zhang, Q Shen, Z Zhu, J Zhang… - Frontiers in Cell and …, 2021 - frontiersin.org
Porcine-induced pluripotent stem cells (piPSCs) could serve as a great model system for
human stem cell preclinical research. However, the pluripotency gene network of piPSCs …
human stem cell preclinical research. However, the pluripotency gene network of piPSCs …
Phosphorylation of NANOG by casein kinase I regulates embryonic stem cell self‐renewal
NP Mullin, J Varghese, D Colby, JM Richardson… - FEBS …, 2021 - Wiley Online Library
The self‐renewal efficiency of mouse embryonic stem cells (ESCs) is determined by the
concentration of the transcription factor NANOG. While NANOG binds thousands of sites in …
concentration of the transcription factor NANOG. While NANOG binds thousands of sites in …
Fine particulate matter reduces the pluripotency and proliferation of human embryonic stem cells through ROS induced AKT and ERK signaling pathway
S Bi, J Tang, L Zhang, L Huang, J Chen, Z Wang… - Reproductive …, 2020 - Elsevier
Epidemiological investigations have found that air fine particulate matter (PM) exposure not
only causes respiratory and cardiovascular diseases in adults and children, but also affects …
only causes respiratory and cardiovascular diseases in adults and children, but also affects …
[HTML][HTML] Inhibition of PKCε induces primordial germ cell reprogramming into pluripotency by HIF1&2 upregulation and histone acetylation
A Moratilla, DS de la Maza, MC Martin… - American Journal of …, 2021 - ncbi.nlm.nih.gov
Historically, primordial germ cells (PGCs) have been a good model to study pluripotency.
Despite their low numbers and limited accessibility in the mouse embryo, they can be easily …
Despite their low numbers and limited accessibility in the mouse embryo, they can be easily …
Structural characterization of stem cell factors Oct4, Sox2, Nanog and Esrrb disordered domains, and a method to identify their phospho-dependent binding partners
B Chafiaa, R Ghouil, A Alik, D Florent, L Damarys… - BioRxiv, 2023 - biorxiv.org
The combined expression of a handful of pluripotency transcription factors (PluriTFs) in
somatic cells can generate induced pluripotent stem cells (iPSCs). Here, we report the …
somatic cells can generate induced pluripotent stem cells (iPSCs). Here, we report the …