Atherosclerosis (AS) is the main pathological basis of cardiovascular diseases, which is
mainly characterized by lipid deposition and inflammatory response. Macrophages (MΦ), as …

Brazilian arnicas belong to the Asteraceae family and can be mainly found in the Brazilian
biome Cerrado (savanna) but also Caatinga, Atlantic Forest, Pampa, Pantanal, and …

Introduction Leishmaniasis is a neglected tropical disease, with approximately 1 million new
cases and 30,000 deaths reported every year worldwide. Given the lack of adequate …

In this work, we investigated in vitro the antioxidant, cytotoxic and anti-leishmanial activities
of a lignin extracted from the leaves of Morinda citrifolia. Initially, an analysis of the …

Leishmaniasis, a neglected tropical disease, still remains a global concern for the
healthcare sector. The primary causative agents of the disease comprise diverse …

Leishmaniasis is a neglected tropical disease with a wide spectrum of clinical
manifestations, ranging from visceral to cutaneous, with millions of new cases and …

Toxoplasma gondii is a protozoan parasite that can cause severe and debilitating diseases,
especially in immunocompromised individuals. The available treatment is based on drugs …

In this study, we have screened a large number of Food and Drug Administration‐approved
compounds for novel anti‐leishmanial molecules targeting the citrate synthase enzyme of …

Protozoan parasites interact with a wide variety of organisms ranging from bacteria to
humans, representing one of the most common causes of parasitic diseases and an …

A growing number of studies have demonstrated the in vitro potential of an impressive
number of antileishmanial candidates in the past years. However, the lack of uniformity …