Sarcopenia, an age-associated decline in skeletal muscle mass coupled with functional
deterioration, may be exacerbated by obesity leading to higher disability, frailty, morbidity …

Helicobacter pylori (H. pylori) is present in roughly 50% of the human population worldwide
and infection levels reach over 70% in developing countries. The infection has classically …

T cells represent a critical effector of cell-mediated immunity. Activated T cells engage in
metabolic reprogramming during effector differentiation to accommodate dynamic changes …

Although a critical role of adaptive immune system has been confirmed in driving local and
systemic inflammation in type 2 diabetes and promoting insulin resistance, the underlying …

Diabetes mellitus (DM) is a serious medical problem affecting millions of peoples worldwide,
and has a great socio-economic impacts. Cytokines possess a pivotal role in modulation of …

Diabetes belongs to a group of metabolic disorders characterized by long term high blood
glucose levels due to either inadequate production of insulin (Type 1 diabetes, T1DM) or …

Microplastics (MPs) as emerging contaminants have become a global environmental
problem. However, studies on the effects of MPs on metabolic diseases remain limited …

BACKGROUND Diabetic foot ulcers are a common diabetic complication leading to
alarming figures of amputation, disability, and early mortality. The diabetic glucooxidative …

Serotonin, also known as 5-hydroxytryptamine (5-HT) is a signaling mediator that regulates
emotion, behavior, and cognition. Previous studies have focused more on the roles of 5-HT …

Obesity-related insulin resistance is driven by low-grade chronic inflammation of metabolic
tissues. In the liver, nonalcoholic fatty liver disease (NAFLD) is associated with hepatic …