Endogenous retroviruses (ERVs) are emerging as promising therapeutic targets in cancer.
As remnants of ancient retroviral infections, ERV-derived regulatory elements coordinate …

The fact that transposable elements (TEs) can influence host gene expression was first
recognized more than 50 years ago. However, since that time, TEs have been widely …

Abstract Background Human endogenous retroviruses (HERVs) represent the inheritance of
ancient germ-line cell infections by exogenous retroviruses and the subsequent …

Transposable elements (TEs) have been shown to contain functional binding sites for
certain transcription factors (TFs). However, the extent to which TEs contribute to the …

Apolipoprotein C1 (apoC1), the smallest of all apolipoproteins, participates in lipid transport
and metabolism. In humans, APOC1 gene is in linkage disequilibrium with APOE gene on …

Several recent reviews surveying the promising field of nutrigenomics 1, 2 have not
discussed the important role that epigenetic mechanisms play at the nexus between nutrition …

For millions of years, retroviral infections have challenged vertebrates, occasionally leading
to germline integration and inheritance as ERVs, genetic parasites whose remnants today …

Retrotransposons are a principal component of most eukaryotic genomes, representing
roughly 40% of the human genome 1 and 50–80% of some grass genomes 2. They are …

Retroelements constitute a large portion of our genomes. One class of these elements, the
human endogenous retroviruses (HERVs), is comprised of remnants of ancient exogenous …

Multiple sclerosis (MS) is an immune inflammatory disease, where the underlying etiological
cause remains elusive. Multiple triggering factors have been suggested, including …