Melioidosis

WJ Wiersinga, HS Virk, AG Torres, BJ Currie… - Nature reviews Disease …, 2018 - nature.com
Burkholderia pseudomallei is a Gram-negative environmental bacterium and the
aetiological agent of melioidosis, a life-threatening infection that is estimated to account …

Pathogens penetrating the central nervous system: infection pathways and the cellular and molecular mechanisms of invasion

SJ Dando, A Mackay-Sim, R Norton… - Clinical microbiology …, 2014 - Am Soc Microbiol
The brain is well protected against microbial invasion by cellular barriers, such as the blood-
brain barrier (BBB) and the blood-cerebrospinal fluid barrier (BCSFB). In addition, cells …

Melioidosis: insights into the pathogenicity of Burkholderia pseudomallei

WJ Wiersinga, T Van der Poll, NJ White… - Nature Reviews …, 2006 - nature.com
Burkholderia pseudomallei is a potential bioterror agent and the causative agent of
melioidosis, a severe disease that is endemic in areas of Southeast Asia and Northern …

Molecular Insights into Burkholderia pseudomallei and Burkholderia mallei Pathogenesis

EE Galyov, PJ Brett, D DeShazer - Annual review of …, 2010 - annualreviews.org
Burkholderia pseudomallei and Burkholderia mallei are closely related gram-negative
bacteria that can cause serious diseases in humans and animals. This review summarizes …

Human melioidosis

I Gassiep, M Armstrong, R Norton - Clinical microbiology reviews, 2020 - Am Soc Microbiol
The causative agent of melioidosis, Burkholderia pseudomallei, a tier 1 select agent, is
endemic in Southeast Asia and northern Australia, with increased incidence associated with …

Pathogenicity and virulence of Burkholderia pseudomallei

NM Bzdyl, CL Moran, J Bendo, M Sarkar-Tyson - Virulence, 2022 - Taylor & Francis
The soil saprophyte, Burkholderia pseudomallei, is the causative agent of melioidosis, a
disease endemic in South East Asia and northern Australia. Exposure to B. pseudomallei by …

Bacterial mycophagy: definition and diagnosis of a unique bacterial–fungal interaction

JHJ Leveau, GM Preston - New Phytologist, 2008 - Wiley Online Library
This review analyses the phenomenon of bacterial mycophagy, which we define as a set of
phenotypic behaviours that enable bacteria to obtain nutrients from living fungi and thus …

The molecular and cellular basis of pathogenesis in melioidosis: how does Burkholderia pseudomallei cause disease?

NR Lazar Adler, B Govan, M Cullinane… - FEMS microbiology …, 2009 - academic.oup.com
Melioidosis, a febrile illness with disease states ranging from acute pneumonia or
septicaemia to chronic abscesses, was first documented by). The causative agent …

Strategies for Intracellular Survival of Burkholderia pseudomallei

EM Allwood, RJ Devenish, M Prescott, B Adler… - Frontiers in …, 2011 - frontiersin.org
Burkholderia pseudomallei is the causative agent of melioidosis, a disease with high
mortality that is prevalent in tropical regions of the world. A key component of the …

Biological Relevance of Colony Morphology and Phenotypic Switching by Burkholderia pseudomallei

N Chantratita, V Wuthiekanun… - Journal of …, 2007 - Am Soc Microbiol
Melioidosis is a notoriously protracted illness and is difficult to cure. We hypothesize that the
causative organism, Burkholderia pseudomallei, undergoes a process of adaptation …