Preparation and application of pH-responsive drug delivery systems

H Ding, P Tan, S Fu, X Tian, H Zhang, X Ma… - Journal of Controlled …, 2022 - Elsevier
Microenvironment-responsive drug delivery systems (DDSs) can achieve targeted drug
delivery, reduce drug side effects and improve drug efficacies. Among them, pH-responsive …

Coating materials to increase the stability of liposomes

D Pasarin, AI Ghizdareanu, CE Enascuta, CB Matei… - Polymers, 2023 - mdpi.com
Liposomes carry various compounds with applications in pharmaceutical, food, and
cosmetic fields, and the administration route is especially parenteral, oral, or transdermal …

Magnetically steerable bacterial microrobots moving in 3D biological matrices for stimuli-responsive cargo delivery

MB Akolpoglu, Y Alapan, NO Dogan, SF Baltaci… - Science …, 2022 - science.org
Bacterial biohybrids, composed of self-propelling bacteria carrying micro/nanoscale
materials, can deliver their payload to specific regions under magnetic control, enabling …

Liposomes: preparation, characteristics, and application strategies in analytical chemistry

G Liu, S Hou, P Tong, J Li - Critical reviews in analytical chemistry, 2022 - Taylor & Francis
In recent years, the application of liposomes in the field of analytical chemistry has attracted
more and more attention. In this paper, the preparation and characterization of liposomes …

What we need to know about liposomes as drug nanocarriers: an updated review

H Abbasi, M Kouchak, Z Mirveis… - Advanced …, 2022 - pmc.ncbi.nlm.nih.gov
Liposomes have been attracted considerable attention as phospholipid spherical vesicles,
over the past 40 years. These lipid vesicles are valued in biomedical application due to their …

Permeation enhancers loaded bilosomes for improved intestinal absorption and cytotoxic activity of doxorubicin

AA Sultan, GA Saad, GM El Maghraby - International Journal of …, 2023 - Elsevier
The clinical utility of doxorubicin is compromised due to dose related toxic side effects and
limited oral bioavailability with no oral formulation being marketed. Enhancement of …

Coacervation‐Driven Semipermeable Nanoreactors for Enzymatic Cascade‐Mediated Cancer Combination Therapy with Enhanced Efficacy

M Lin, X Lv, H Wang, L Shu, H Wang… - Advanced …, 2024 - Wiley Online Library
Utilizing enzyme cascades as a promising approach for targeted cancer therapies holds
significant potential, yet its clinical effectiveness is substantially hindered by functional …

Aptamer-functionalized pH-sensitive liposomes for a selective delivery of echinomycin into cancer cells

Z Lafi, W Alshaer, MH Ma'mon, M Zihlif, DA Alqudah… - RSC …, 2021 - pubs.rsc.org
Echinomycin (quinomycin A) is a peptide antibiotic from the quinoxaline family, which has a
DNA bifunctional intercalating activity and an inhibitor of hypoxia-inducible factor (HIF1α) …

Quality by design approach in liposomal formulations: Robust product development

W Alshaer, H Nsairat, Z Lafi, OM Hourani, A Al-Kadash… - Molecules, 2022 - mdpi.com
Nanomedicine is an emerging field with continuous growth and differentiation. Liposomal
formulations are a major platform in nanomedicine, with more than fifteen FDA-approved …

Cellular Membrane‐Engineered Nanovesicles as a Three‐Stage Booster to Target the Lesion Core

F Huang, Y Du, Y Chen, Z Qiu, Z Wang… - Advanced …, 2023 - Wiley Online Library
The lesion core is the area with the most serious injury and vigorous repair. Existing
nanocarriers are difficult to break through the targeted delivery to the lesion core for precise …