Reactive oxygen species signalling in plant stress responses

R Mittler, SI Zandalinas, Y Fichman… - … reviews Molecular cell …, 2022 - nature.com
Reactive oxygen species (ROS) are key signalling molecules that enable cells to rapidly
respond to different stimuli. In plants, ROS play a crucial role in abiotic and biotic stress …

Stress-induced reactive oxygen species compartmentalization, perception and signalling

B Castro, M Citterico, S Kimura, DM Stevens… - Nature plants, 2021 - nature.com
Reactive oxygen species (ROS) are essential for life and are involved in the regulation of
almost all biological processes. ROS production is critical for plant development, response …

Cysteine oxidation in proteins: structure, biophysics, and simulation

D Garrido Ruiz, A Sandoval-Perez, AV Rangarajan… - Biochemistry, 2022 - ACS Publications
Cysteine side chains can exist in distinct oxidation states depending on the pH and redox
potential of the environment, and cysteine oxidation plays important yet complex regulatory …

[HTML][HTML] How are hydrogen peroxide messages relayed to affect cell signalling?

EA Veal, P Kritsiligkou - Current opinion in chemical biology, 2024 - Elsevier
H 2 O 2 signals trigger adaptive responses affecting cell division, differentiation, migration,
and survival. These signals are transduced by selective oxidation of cysteines on specific …

A critical evaluation of protein kinase regulation by activation loop autophosphorylation

R Reinhardt, TA Leonard - Elife, 2023 - elifesciences.org
Phosphorylation of proteins is a ubiquitous mechanism of regulating their function,
localization, or activity. Protein kinases, enzymes that use ATP to phosphorylate protein …

Phosphorylated transcription factor PuHB40 mediates ROS-dependent anthocyanin biosynthesis in pear exposed to high light

L Zhang, L Wang, Y Fang, Y Gao, S Yang, J Su… - The Plant …, 2024 - academic.oup.com
Plants are increasingly vulnerable to environmental stresses because of global warming
and climate change. Stress-induced reactive oxygen species (ROS) accumulation results in …

Oxygen-dependent changes in binding partners and post-translational modifications regulate the abundance and activity of HIF-1α/2α

LA Daly, PJ Brownridge, M Batie, S Rocha, V Sée… - Science …, 2021 - science.org
Cellular adaptation to low-oxygen environments is mediated in part by the hypoxia-inducible
factors (HIFs). Like other transcription factors, the stability and transcriptional activity of HIFs …

Custom workflow for the confident identification of sulfotyrosine-containing peptides and their discrimination from phosphopeptides

LA Daly, DP Byrne, S Perkins… - Journal of Proteome …, 2023 - ACS Publications
Protein tyrosine sulfation (sY) is a post-translational modification (PTM) catalyzed by Golgi-
resident tyrosyl protein sulfo transferases (TPSTs). Information on sY in humans is currently …

[HTML][HTML] Aurora A kinase activation: Different means to different ends

N Tavernier, F Sicheri, L Pintard - The Journal of cell biology, 2021 - ncbi.nlm.nih.gov
Aurora A is a serine/threonine kinase essential for mitotic entry and spindle assembly.
Recent molecular studies have revealed the existence of multiple, distinct mechanisms of …

[HTML][HTML] Emerging roles of Aurora-A kinase in cancer therapy resistance

D Zheng, J Li, H Yan, G Zhang, W Li, E Chu… - … Pharmaceutica Sinica B, 2023 - Elsevier
Abstract Aurora kinase A (Aurora-A), a serine/threonine kinase, plays a pivotal role in
various cellular processes, including mitotic entry, centrosome maturation and spindle …