Coordinating properties of peptides containing histidyl residues
Numerous studies have demonstrated the high metal binding capacity and selectivity of
peptide molecules. The terminal amino group, deprotonated amide nitrogens, and various …
peptide molecules. The terminal amino group, deprotonated amide nitrogens, and various …
Competition between Cd (II) and other divalent transition metal ions during complex formation with amino acids, peptides, and chelating agents
Cadmium is not an essential element for humans, but instead its compounds are known for
their toxicity. In addition to the risks for workers in industries that use cadmium, this metal can …
their toxicity. In addition to the risks for workers in industries that use cadmium, this metal can …
The metal loading ability of β-amyloid N-terminus: a combined potentiometric and spectroscopic study of copper (II) complexes with β-amyloid (1− 16), its Short or …
Alzheimer's disease (AD) is becoming a rapidly growing health problem, as it is one of the
main causes of dementia in the elderly. Interestingly, copper (II)(together with zinc and iron) …
main causes of dementia in the elderly. Interestingly, copper (II)(together with zinc and iron) …
Copper (II) interaction with prion peptide fragments encompassing histidine residues within and outside the octarepeat domain: speciation, stability constants and …
A 31‐mer polypeptide, which encompasses residues 84–114 of human prion protein HuPrP
(84–114) and contains three histidyl residues, namely one from the octarepeat (His85) and …
(84–114) and contains three histidyl residues, namely one from the octarepeat (His85) and …
Modulating the aggregation of human prion protein PrP 106–126 by an indole-based cyclometallated palladium complex
The spontaneous aggregation of infectious or misfolded forms of prion protein is known to
be responsible for neurotoxicity in brain cells, which ultimately leads to the progression of …
be responsible for neurotoxicity in brain cells, which ultimately leads to the progression of …
Unravelling the Mystery of COVID‐19 Pathogenesis: Spike Protein and Cu Can Synergize to Trigger ROS Production
M Katarzyna Lesiów, M Witwicki, NK Tan… - … A European Journal, 2023 - Wiley Online Library
The COVID‐19 pandemic has had a devastating impact on global health, highlighting the
need to understand how the SARS‐CoV‐2 virus damages the lungs in order to develop …
need to understand how the SARS‐CoV‐2 virus damages the lungs in order to develop …
Interactions of Cu2+ with prion family peptide fragments: Considerations on affinity, speciation and coordination
The review describes the stability and the coordination modes of Cu2+ complexes with
different regions of N-terminus prion proteins. The structural features of the different metal …
different regions of N-terminus prion proteins. The structural features of the different metal …
Prion proteins and copper ions. Biological and chemical controversies
H Kozlowski, M Łuczkowski, M Remelli - Dalton Transactions, 2010 - pubs.rsc.org
The Prion protein (PrPc) involvement in some neurodegenerative diseases is well assessed
although its “normal” biological role is not completely understood. It is known that PrPC can …
although its “normal” biological role is not completely understood. It is known that PrPC can …
Synthesis of inorganic nanomaterials mediated by protein assemblies
SS Behrens - Journal of Materials Chemistry, 2008 - pubs.rsc.org
Biological materials naturally display a variety of functional structures highly organized at the
nanoscale. Various bioassemblies have been shown to template complex, multidimensional …
nanoscale. Various bioassemblies have been shown to template complex, multidimensional …
[HTML][HTML] Empirical rules for rationalising visible circular dichroism of Cu2+ and Ni2+ histidine complexes: applications to the prion protein
M Klewpatinond, JH Viles - FEBS letters, 2007 - Elsevier
A natively unfolded region of the prion protein, PrP (90–126) binds Cu2+ ions and is vital for
prion propagation. Pentapeptides, acyl-GGGTH92–96 and acyl-TNMKH107–111, represent …
prion propagation. Pentapeptides, acyl-GGGTH92–96 and acyl-TNMKH107–111, represent …