Computational network inference for bacterial interactomics

K James, J Muñoz-Muñoz - Msystems, 2022 - Am Soc Microbiol
Since the large-scale experimental characterization of protein–protein interactions (PPIs) is
not possible for all species, several computational PPI prediction methods have been …

Identifying drug targets in pancreatic ductal adenocarcinoma through machine learning, analyzing biomolecular networks, and structural modeling

W Yan, X Liu, Y Wang, S Han, F Wang, X Liu… - Frontiers in …, 2020 - frontiersin.org
Pancreatic ductal adenocarcinoma (PDAC) is one of the leading causes of cancer-related
death and has an extremely poor prognosis. Thus, identifying new disease-associated …

[PDF][PDF] 肺和肠道微生物群落与哮喘的研究进展

李了, 杨磊 - 中国医药导报, 2022 - yiyaodaobao.com.cn
X 喘是种常见的慢性呼吸系统疾病发病率呈逐年上升的趋势其临床特征及免疫学和分子病因学
往往因人而异近些年随着微生物代谢组学分析的兴起临床中发现肺和肠道微生物群落在健康 …

Protein Integrated Network Analysis to Reveal Potential Drug Targets Against Extended Drug-Resistant Mycobacterium tuberculosis XDR1219

NUA Zahra, F Jamil, R Uddin - Molecular Biotechnology, 2021 - Springer
The reconstruction and analysis of the protein–protein interaction (PPI) network is a powerful
approach to understand the complex biological and molecular functions in normal and …

[HTML][HTML] Common genes involved in autophagy, cellular senescence and the inflammatory response in AMD and drug discovery identified via biomedical databases

S Wang, C Liu, W Ouyang, Y Liu, C Li… - … Vision Science & …, 2021 - iovs.arvojournals.org
Purpose: Retinal pigment epithelial cell autophagy dysfunction, cellular senescence, and
the retinal inflammatory response are key pathogenic factors in age-related macular …

Protein–protein interaction network and potential drug target candidates of Streptococcus suis

MF Tan, G Zou, Y Wei, WQ Liu, HQ Li… - Journal of Applied …, 2021 - academic.oup.com
Aims This study aimed to explore potential drug targets of Streptococcus suis at the system
level. Methods and Results A homologous protein mapping method was used in the …

Data-Driven and Artificial Intelligence Approaches for System-Wide Prediction of the Drugable Proteome to Drug Discovery in Farm Animals

AS Ben Geoffrey, JS Virk, D Mittal, G Kaur… - … : Animal Biotechnology for …, 2024 - Springer
A druggable proteome is of global interest for the drug development process. Growing
livestock for food relies strongly on pharmacologically active chemicals, or medicines, in …