The Simpson grading: is it still valid?

S Chotai, TH Schwartz - Cancers, 2022 - mdpi.com
Simple Summary Since the initial publication of the Simpson Grade scale, the management
paradigm for intracranial meningiomas has significantly evolved. The generalized …

An interpretable radiomics model to select patients for radiotherapy after surgery for WHO grade 2 meningiomas

CJ Park, SH Choi, J Eom, HK Byun, SS Ahn… - Radiation …, 2022 - Springer
Objectives This study investigated whether radiomic features can improve the prediction
accuracy for tumor recurrence over clinicopathological features and if these features can be …

Somatostatin receptor–targeted radiopeptide therapy in treatment-refractory meningioma: Individual patient data meta-analysis

C Mirian, AK Duun-Henriksen, A Maier… - Journal of Nuclear …, 2021 - Soc Nuclear Med
Somatostatin receptor (SSTR)–targeted peptide receptor radionuclide therapy (PRRT)
represents a promising approach for treatment-refractory meningiomas. Methods: We …

Machine learning using multiparametric magnetic resonance imaging radiomic feature analysis to predict Ki-67 in World Health Organization grade I meningiomas

O Khanna, AF Kazerooni, CJ Farrell… - …, 2021 - journals.lww.com
BACKGROUND Although World Health Organization (WHO) grade I meningiomas are
considered “benign” tumors, an elevated Ki-67 is one crucial factor that has been shown to …

TERT promoter mutations in primary and secondary WHO grade III meningioma

AD Maier, A Stenman, F Svahn, C Mirian… - Brain …, 2021 - Wiley Online Library
Purpose: TERT promoter mutation (TERTpMut) has a strong association to recurrence and
has been suggested to act as a driver mutation for malignant transformation of WHO grade I …

Long-term follow-up and predictors of functional outcome after surgery for spinal meningiomas: a population-based cohort study

J Pettersson-Segerlind, A Fletcher-Sandersjöö… - Cancers, 2021 - mdpi.com
Simple Summary Spinal meningiomas are the most common adult primary intradural spinal
tumors. While mostly benign, they may give rise to spinal cord compression with acute or …

Proposal of a new grading system for meningioma resection: the Copenhagen Protocol

J Haslund-Vinding, J Skjoth-Rasmussen… - Acta …, 2022 - Springer
Introduction The extent of meningioma resection is the most fundamental risk factor for
recurrence, and exact knowledge of extent of resection is necessary for prognostication and …

Clinical significance of NF2 alteration in grade I meningiomas revisited; prognostic impact integrated with extent of resection, tumour location, and Ki-67 index

Y Teranishi, A Okano, S Miyawaki, K Ohara… - Acta Neuropathologica …, 2022 - Springer
NF2 alteration is the most commonly–found genetic abnormality in meningiomas and is
known to initiate events for aggressive-type meningiomas. Whereas the prognosis of …

An integrative non-invasive malignant brain tumors classification and Ki-67 labeling index prediction pipeline with radiomics approach

L Zhang, X Liu, X Xu, W Liu, Y Jia, W Chen, X Fu… - European Journal of …, 2023 - Elsevier
Background The histological sub-classes of brain tumors and the Ki-67 labeling index (LI) of
tumor cells are major factors in the diagnosis, prognosis, and treatment management of …

Gene expression analysis during progression of malignant meningioma compared to benign meningioma

AD Maier, A Meddis, C Mirian, J Haslund-Vinding… - Journal of …, 2022 - thejns.org
OBJECTIVE Meningioma is the most common primary intracranial neoplasm. Only 1%–3%
of meningiomas are malignant according to the 2016 WHO criteria (WHO grade III). High …