A comprehensive reference and teaching aid on tissue engineering—covering everything
from the basics of regenerative medicine to more advanced and forward thinking topics such …

Advanced medical devices, treatments and therapies demand an understanding of the role
of interfacial properties on the cellular response. This is particularly important in the …

Background: Hepatic oval cells, progenitor cells in the liver, can differentiate into
hepatocytes and bile duct cells both in vitro and in vivo. Although hepatic stellate cells are …

1. Glutaric acidemia type I (GA I) is a neurometabolic disorder caused by deficiency of
glutaryl-CoA dehydrogenase, which leads to tissue accumulation of predominantly glutaric …

Tissue accumulation of α-ketoadipic (KAA) and α-aminoadipic (AAA) acids is the
biochemical hallmark of α-ketoadipic aciduria. This inborn error of metabolism is currently …

BACKGROUND: Liver resection is a feasible treatment for multiple liver diseases. There is
no evidence about the impact of age on liver regeneration. OBJECTIVE: To assess the effect …

Animal models of inborn errors of metabolism are useful for investigating the pathogenesis
associated with the corresponding human disease. Since the mechanisms involved in the …

Purpose To investigate the effects of pine needle extract (PNE) on the expression of
proliferating cell nuclear antigen (PCNA) and Ki-67 during liver regeneration induced by …

The present work investigated the in vitro effects of 3-hydroxy-3-methylglutarate, 3-
methylglutarate, 3-methylglutaconate and 3-hydroxyisovalerate, which accumulate in 3 …

The decomposition of solid waste in landfill is responsible for the formation of leachate, a
dark liquid with an unpleasant odor; studies investigating its toxicity on mammals are rare …