Transition metal-catalysed C–H activation has emerged as an increasingly powerful platform
for molecular syntheses, enabling applications to natural product syntheses, late-stage …

Biocatalysis, using defined enzymes for organic transformations, has become a common
tool in organic synthesis, which is also frequently applied in industry. The generally high …

Enzymes are excellent catalysts that are increasingly being used in industry and academia.
This perspective is primarily aimed at synthetic organic chemists with limited experience …

The use of plant secondary metabolites has gained considerable attention among clinicians
in the prevention and treatment of cancer. A secondary metabolite isolated mainly from the …

The use of enzyme-mediated reactions has transcended ancient food production to the
laboratory synthesis of complex molecules. This evolution has been accelerated by …

Covering: up to 2022 Podophyllotoxin (PTOX, 1), a kind of aryltetralin-type lignan, was first
discovered in the plant Podophyllum peltatum and its structure was clarified by W. Borsche …

Enzymes exercise impeccable control over chemoselectivity, site selectivity and
stereoselectivity in reactions they mediate, such that we have witnessed a surge in the …

Conspectus Biocatalytic transformations that leverage the selectivity and efficiency of
enzymes represent powerful tools for the construction of complex natural products. Enabled …

Etoposide is a plant-derived drug used clinically to treat several forms of cancer. Recent
shortages of etoposide demonstrate the need for a more dependable production method to …

With recent outbreaks of COVID-19 and Ebola, health and healthcare have once more
shown to be heavily burdened by the lack of generally effective anti-viral therapies. Initial …