Current immunotherapy approaches in non-Hodgkin lymphomas

R Pytlik, K Polgarova, J Karolova, P Klener - Vaccines, 2020 - mdpi.com
Non-Hodgkin lymphomas (NHLs) are lymphoid malignancies of B-or T-cell origin. Despite
great advances in treatment options and significant improvement of survival parameters, a …

Development and characterization of ibrutinib-loaded ethylcellulose-based nanosponges: Cytotoxicity assay against MCF-7 cell lines

F Fatima, MK Anwer - Applied Sciences, 2023 - mdpi.com
Ibrutinib (ITB) is a specific and novel irreversible inhibitor of Bruton's tyrosine kinase
enzyme, for which reason it exhibits potential chemotherapeutic effects against a few types …

Incidence and associated risk factors for invasive fungal infections and other serious infections in patients on ibrutinib

T Holowka, H Cheung, M Malinis, G Gan… - Journal of Infection and …, 2021 - Elsevier
Background Ibrutinib is a small molecule tyrosine kinase inhibitor that blocks the activity of B
cells and other immune effectors and is used in a variety of hematologic malignancies …

Management of relapsed hairy cell leukemia: a systematic review of novel agents and targeted therapies

R Siddiqui, M Sardar, M Shahzad, J Jose… - … Myeloma and Leukemia, 2021 - Elsevier
Background: Hairy cell leukemia (HCL) responds well to purine analogs with an overall
median relapse free survival of 11-16 years. Most patients can be retreated with the same or …

[PDF][PDF] Modelling the ability of targeted drugs and immunotherapy to modulate anti-tumour T cell activity in Chronic Lymphocytic Leukaemia

D Papazoglou - 2022 - kclpure.kcl.ac.uk
PDX Patient-derived xenograft PD-1 Programmed cell death protein 1 PD-L1 Programmed
cell death-Ligand 1 PD-L2 Programmed cell death-Ligand 2 PDGF Platelet-derived growth …

Bruton tyrosine kinase inhibitors for chronic lymphocytic leukemia

Cochrane Haematology Group… - Cochrane Database …, 1996 - cochranelibrary.com
Objectives This is a protocol for a Cochrane Review (intervention). The objectives are as
follows: The objective of this review is to assess the effects of Bruton tyrosine kinase (BTK) …