[HTML][HTML] Mechanisms of macular edema: beyond the surface

A Daruich, A Matet, A Moulin, L Kowalczuk… - Progress in retinal and …, 2018 - Elsevier
Macular edema consists of intra-or subretinal fluid accumulation in the macular region. It
occurs during the course of numerous retinal disorders and can cause severe impairment of …

Inflammation and its role in age-related macular degeneration

A Kauppinen, JJ Paterno, J Blasiak, A Salminen… - Cellular and molecular …, 2016 - Springer
Inflammation is a cellular response to factors that challenge the homeostasis of cells and
tissues. Cell-associated and soluble pattern-recognition receptors, eg Toll-like receptors …

Quercetin inhibits the production of IL-1β-induced inflammatory cytokines and chemokines in ARPE-19 cells via the MAPK and NF-κB signaling pathways

SC Cheng, WC Huang, JH S. Pang, YH Wu… - International journal of …, 2019 - mdpi.com
Quercetin, a bioflavonoid derived from vegetables and fruits, exerts anti-inflammatory effects
in various diseases. Our previous study revealed that quercetin could suppress the …

Mitogen-activated protein kinases as therapeutic targets for asthma

MH Khorasanizadeh, M Eskian, EW Gelfand… - Pharmacology & …, 2017 - Elsevier
Corticosteroid-resistant asthmatics, although comprising only a portion of the asthma
population, account for most of the morbidity, mortality and economic burden associated with …

Anti-inflammatory property of quercetin through downregulation of ICAM-1 and MMP-9 in TNF-α-activated retinal pigment epithelial cells

SC Cheng, YH Wu, WC Huang, JHS Pang, TH Huang… - Cytokine, 2019 - Elsevier
Quercetin is a flavonoid polyphenolic compound present in fruits and vegetables that has
proven anti-inflammatory activity. The goal of the present investigation was to investigate the …

High glucose promotes the migration of retinal pigment epithelial cells through increased oxidative stress and PEDF expression

M Farnoodian, C Halbach, C Slinger… - … of Physiology-Cell …, 2016 - journals.physiology.org
Defects in the outer blood-retinal barrier have significant impact on the pathogenesis of
diabetic retinopathy and macular edema. However, the detailed mechanisms involved …

Comparing the efficacy of dexamethasone implant and anti-VEGF for the treatment of macular edema: A systematic review and meta-analysis

H Tang, J Li, Y Yuan, Y Ling, Z Mei, H Zou - Plos one, 2024 - journals.plos.org
Objectives To evaluate the clinical efficacy of dexamethasone (DEX) implant, for the
treatment of macular edema (ME) caused by retinal vein occlusion (RVO) and diabetic …

Hydroxysafflor yellow A alleviates ovalbumin-induced asthma in a Guinea pig model by attenuateing the expression of inflammatory cytokines and signal transduction

M Zheng, X Guo, R Pan, J Gao, B Zang… - Frontiers in …, 2019 - frontiersin.org
Hydroxysafflor yellow A (HSYA) is an effective ingredient of the Chinese herb Carthamus
tinctorius L. In this study, we aimed to evaluate the effects of HSYA on ovalbumin (OVA) …

[HTML][HTML] VEGFR2 promotes central endothelial activation and the spread of pain in inflammatory arthritis

N Beazley-Long, D Hodge, WR Ashby… - Brain, behavior, and …, 2018 - Elsevier
Chronic pain can develop in response to conditions such as inflammatory arthritis. The
central mechanisms underlying the development and maintenance of chronic pain in …

Lysophosphatidic acid is a proinflammatory stimulus of renal tubular epithelial cells

C Magkrioti, G Antonopoulou, D Fanidis… - International Journal of …, 2022 - mdpi.com
Chronic kidney disease (CKD) refers to a spectrum of diseases defined by renal fibrosis,
permanent alterations in kidney structure, and low glomerular-filtration rate. Prolonged …