Doxorubicin (Dox) is a secondary metabolite of the mutated strain of Streptomyces peucetius
var. Caesius and belongs to the anthracyclines family. The anti-cancer activity of Dox is …

Nowadays, cardiovascular diseases (CVDs) are a global threat to public health, accounting
for almost one‐third of all deaths worldwide. One of the key mechanistic pathways …

Cancer is a major health concern worldwide as conventional treatment modalities face
several limitations such as drug resistance, toxicity etc. To overcome such deficits …

Doxorubicin (DOX) is an anticancer agent for treating solid and soft tissue malignancies.
However, the clinical use of DOX is restricted by cumulative, dose-dependent cardiotoxicity …

Ferroptosis has been implicated in the therapeutic responses of various types of tumors.
Cyclophosphamide (CTX), one of the most successful antitumor agents, is widely used to …

Hematopoietic stem cell transplantation (HSCT) is the only curative treatment for many
patients suffering from hematologic malignancies, solid tumors, inborn errors of metabolism …

The advancement in therapy has provided a dramatic improvement in the rate of recovery
among cancer patients. However, this improved survival is also associated with enhanced …

Advances in the development of anti-tumour drugs and related technologies have resulted
in a significant increase in the number of cancer survivors. However, the incidence of …

Saffron is commonly used in traditional medicines and precious perfumes. It contains
pharmacologically active compounds with notably potent antioxidant activity. Saffron has a …

Aims Cyclophosphamide (CYP) is a potent anticancer agent with well-known cardiotoxicity
that limits its clinical applications. Cilostazol is a vosodilating drug, showing a …