The immunopathophysiology of endometriosis

LK Symons, JE Miller, VR Kay, RM Marks… - Trends in molecular …, 2018 - cell.com
Endometriosis is a chronic, inflammatory, estrogen-dependent disease characterized by the
growth of endometrial tissue outside of the uterine cavity. Although the etiology of …

Recent advances in the application of mesoporous silica-based nanomaterials for bone tissue engineering

R Eivazzadeh-Keihan, KK Chenab… - Materials Science and …, 2020 - Elsevier
Silica nanomaterials (SNMs) and their composites have recently been investigated as
scaffolds for bone tissue engineering. SNM scaffolds possess the ability to encourage bone …

[HTML][HTML] Oxygen in stem cell biology: a critical component of the stem cell niche

A Mohyeldin, T Garzón-Muvdi, A Quiñones-Hinojosa - Cell stem cell, 2010 - cell.com
The defining hallmark of stem cells is their ability to self-renew and maintain multipotency.
This capacity depends on the balance of complex signals in their microenvironment. Low …

Origin and physiological roles of inflammation

R Medzhitov - Nature, 2008 - nature.com
Inflammation underlies a wide variety of physiological and pathological processes. Although
the pathological aspects of many types of inflammation are well appreciated, their …

Hypoxia-induced pulmonary vascular remodeling: cellular and molecular mechanisms

KR Stenmark, KA Fagan, MG Frid - Circulation research, 2006 - Am Heart Assoc
Chronic hypoxic exposure induces changes in the structure of pulmonary arteries, as well as
in the biochemical and functional phenotypes of each of the vascular cell types, from the …

The pathogenesis of adenomyosis vis-à-vis endometriosis

SW Guo - Journal of clinical medicine, 2020 - mdpi.com
Adenomyosis is used to be called endometriosis interna, and deep endometriosis is now
called adenomyosis externa. Thus, there is a question as to whether adenomyosis is simply …

Role of reactive oxygen and nitrogen species in the vascular responses to inflammation

PR Kvietys, DN Granger - Free Radical Biology and Medicine, 2012 - Elsevier
Inflammation is a complex and potentially life-threatening condition that involves the
participation of a variety of chemical mediators, signaling pathways, and cell types. The …

[HTML][HTML] Chronic hypoxia as a mechanism of progression of chronic kidney diseases: from hypothesis to novel therapeutics

LG Fine, JT Norman - Kidney international, 2008 - Elsevier
In chronic kidney disease, functional impairment correlates with tubulointerstitial fibrosis
characterised by inflammation, accumulation of extracellular matrix, tubular atrophy and …

Microparticles, vascular function, and atherothrombosis

PE Rautou, AC Vion, N Amabile, G Chironi… - Circulation …, 2011 - Am Heart Assoc
Membrane-shed submicron microparticles (MPs) are released after cell activation or
apoptosis. High levels of MPs circulate in the blood of patients with atherothrombotic …

Invasive growth: a MET-driven genetic programme for cancer and stem cells

C Boccaccio, PM Comoglio - Nature Reviews Cancer, 2006 - nature.com
Metastasis follows the inappropriate activation of a genetic programme termed invasive
growth, which is a physiological process that occurs during embryonic development and …