Hypertension is a highly prevalent condition with numerous health risks, and the incidence
of hypertension is greatest among older adults. Traditional discussions of hypertension have …

Atherosclerosis is an inflammatory disease. Because high plasma concentrations of
cholesterol, in particular those of low-density lipoprotein (LDL) cholesterol, are one of the …

The concentration of hydrogen peroxide (H 2 O 2) in blood and plasma is a measurement
that has often been made, but the absolute values remain unsettled due the great variability …

Objectives In view of the critical role of intracellular Ca 2+-overload in the genesis of
myocyte dysfunction and the ability of reactive oxygen species (ROS) to induce the …

Hydrogen peroxide (H2O2) is widely regarded as a cytotoxic agent whose levels must be
minimized by the action of antioxidant defence enzymes. In fact, H2O2 is poorly reactive in …

The JmjC domain-containing histone demethylases can remove histone lysine methylation
and thereby regulate gene expression. The JmjC domain uses iron Fe (II) and α …

The question of serum uric acid as an independent risk factor in subjects with essential
hypertension remains controversial. For up to 12 years (mean, 4.0) we followed 1720 …

Increased vascular production of reactive oxygen species (ROS; termed oxidative stress)
has been implicated in various chronic diseases, including hypertension. Oxidative stress is …

Reactive oxygen species (ROS) influence many physiological processes including host
defense, hormone biosynthesis, fertilization, and cellular signaling. Increased ROS …

Lead is an environmentally persistent toxin that causes neurological, hematological,
gastrointestinal, reproductive, circulatory, and immunological pathologies. The propensity for …