Nuclear orpan receptors are members of the superfamily of structurally related, ligand-
inducible transcription factors for which no ligand has yet been identified. Over the past few …

The identification of a common cis-acting silencer element, a neuron-restrictive silencer
element (NRSE), in multiple neuron-specific genes, together with the finding that zinc finger …

Sp1, Sp3 (SPR‐2) and Sp4 (SPR‐1) are human sequence‐specific DNA binding proteins
with very similar structural features. In this report, we have analyzed Sp3 in direct …

The goal of the present study was to determine the molecular mechanism whereby
transforming growth factor β (TGFβ) increases smooth muscle (SM) α-actin expression …

An efficient method of transgene modulation in fertilized eggs has been developed that uses
the Cre/loxP recombination system. Twelve transgenic mouse lines carrying a chicken beta …

The two subtypes of retinoid Z receptor (RZR α and β) and the three splicing variants of
retinoid orphan receptor (ROR α1, α2, and α3) form a subfamily within the superfamily of …

Many important physiological functions are controlled by hormones via binding and
activating members of the nuclear receptor superfamily. This group of structurally related …

The cAMP-dependent protein kinase (PKA) phosphorylates CREB327/341 at a single serine
residue, Ser119/133, respectively. Phosphorylation at this site creates the sequence motif …

The effects of dexamethasone on the growth of four human multiple myeloma cell lines were
studied. In addition, the effects on the expression of interleukin-6 (IL-6) and IL-6 receptor (IL …

The mitochondrial uncoupling protein (UCP) is responsible for the thermogenic function of
brown fat, and it is a molecular marker of the brown adipocyte cell type. Retinoic acid (RA) …