Recurrent topics in mass spectrometry-based metabolomics and lipidomics—standardization, coverage, and throughput
We have come a long way in the last years of developing analytical strategies in
metabolomics. We have seen huge progress in tackling multiplatform measurement, data …
metabolomics. We have seen huge progress in tackling multiplatform measurement, data …
A current encyclopedia of bioinformatics tools, data formats and resources for mass spectrometry lipidomics
N Hoffmann, G Mayer, C Has, D Kopczynski… - Metabolites, 2022 - mdpi.com
Mass spectrometry is a widely used technology to identify and quantify biomolecules such
as lipids, metabolites and proteins necessary for biomedical research. In this study, we …
as lipids, metabolites and proteins necessary for biomedical research. In this study, we …
Antihypertensive activity of oleanolic acid is mediated via downregulation of secretory phospholipase A2 and fatty acid synthase in spontaneously hypertensive rats
S Zhang, Y Liu, X Wang, Z Tian… - International …, 2020 - spandidos-publications.com
Oleanolic acid (OA) is reported to possess antihypertensive activity via the regulation of lipid
metabolism; however, the mechanisms underlying lipid regulation by OA are yet to be fully …
metabolism; however, the mechanisms underlying lipid regulation by OA are yet to be fully …
[HTML][HTML] Alternating in-source fragmentation with single-stage high-resolution mass spectrometry with high annotation confidence in non-targeted metabolomics
Non-targeted metabolomics is increasingly applied in various applications for understanding
biological processes and finding novel biomarkers in living organisms. However, high …
biological processes and finding novel biomarkers in living organisms. However, high …
Opti-nQL: An optimized, versatile and sensitive nano-LC method for MS-based lipidomics analysis
A Cattaneo, G Martano, U Restuccia, L Tronci… - Metabolites, 2021 - mdpi.com
Lipidomics is the comprehensive analysis of lipids in a given biological system. This
investigation is often limited by the low amount and high complexity of biological samples …
investigation is often limited by the low amount and high complexity of biological samples …
Ion entropy and accurate entropy-based FDR estimation in metabolomics
Accurate metabolite annotation and false discovery rate (FDR) control remain challenging in
large-scale metabolomics. Recent progress leveraging proteomics experiences and …
large-scale metabolomics. Recent progress leveraging proteomics experiences and …