Multi-tissue omics analyses reveal molecular regulatory networks for puberty in composite beef cattle
Puberty is a complex physiological event by which animals mature into an adult capable of
sexual reproduction. In order to enhance our understanding of the genes and regulatory …
sexual reproduction. In order to enhance our understanding of the genes and regulatory …
Integrative genomics identifies APOE ε4 effectors in Alzheimer's disease
Late-onset Alzheimer's disease (LOAD) risk is strongly influenced by genetic factors such as
the presence of the apolipoprotein E ε4 allele (referred to here as APOE4), as well as non …
the presence of the apolipoprotein E ε4 allele (referred to here as APOE4), as well as non …
Predicting hub genes associated with cervical cancer through gene co-expression networks
SP Deng, L Zhu, DS Huang - IEEE/ACM Transactions on …, 2015 - ieeexplore.ieee.org
Cervical cancer is the third most common malignancy in women worldwide. It remains a
leading cause of cancer-related death for women in developing countries. In order to …
leading cause of cancer-related death for women in developing countries. In order to …
Integrating gene expression and protein-protein interaction network to prioritize cancer-associated genes
Background To understand the roles they play in complex diseases, genes need to be
investigated in the networks they are involved in. Integration of gene expression and …
investigated in the networks they are involved in. Integration of gene expression and …
Alternative α-synuclein transcript usage as a convergent mechanism in Parkinson's disease pathology
Abstract α-Synuclein is implicated both in physiological functions at neuronal synaptic
terminals as well as in pathological processes in the context of Parkinson's disease …
terminals as well as in pathological processes in the context of Parkinson's disease …
Differential co-expression-based detection of conditional relationships in transcriptional data: comparative analysis and application to breast cancer
Background Elucidation of regulatory networks, including identification of regulatory
mechanisms specific to a given biological context, is a key aim in systems biology. This has …
mechanisms specific to a given biological context, is a key aim in systems biology. This has …
Comparative analysis of muscle transcriptome between pig genotypes identifies genes and regulatory mechanisms associated to growth, fatness and metabolism
Iberian ham production includes both purebred (IB) and Duroc-crossbred (IBxDU) Iberian
pigs, which show important differences in meat quality and production traits, such as muscle …
pigs, which show important differences in meat quality and production traits, such as muscle …
Cerebrum, liver, and muscle regulatory networks uncover maternal nutrition effects in developmental programming of beef cattle during early pregnancy
The molecular basis underlying fetal programming in response to maternal nutrition remains
unclear. Herein, we investigated the regulatory relationships between genes in fetal …
unclear. Herein, we investigated the regulatory relationships between genes in fetal …
Identification of gene networks for residual feed intake in Angus cattle using genomic prediction and RNA-seq
Improvement in feed conversion efficiency can improve the sustainability of beef cattle
production, but genomic selection for feed efficiency affects many underlying molecular …
production, but genomic selection for feed efficiency affects many underlying molecular …
Mining the bladder cancer-associated genes by an integrated strategy for the construction and analysis of differential co-expression networks
SP Deng, L Zhu, DS Huang - BMC genomics, 2015 - Springer
Background Bladder cancer is the most common malignant tumor of the urinary system and
it is a heterogeneous disease with both superficial and invasive growth. However, its …
it is a heterogeneous disease with both superficial and invasive growth. However, its …