Age-related macular degeneration (AMD) is the leading cause of irreversible blindness in
adults over 50 years old. Genetic, epidemiological, and molecular studies are beginning to …

Biomarkers can help unravel mechanisms of disease and identify new targets for therapy.
They can also be useful in clinical practice for monitoring disease progression, evaluation of …

Background Lipid metabolism and particularly high-density lipoprotein (HDL) may be
involved in the pathogenic mechanism of age-related macular degeneration (AMD) …

Lipidomic profiling of plasma is an emerging field, given the importance of lipids in major
cellular pathways, and is dependent on efficient lipid extraction protocols. Recent attention …

Gender medicine has been a major focus of research in recent years. The present review
focuses on gender differences in the epidemiology of the most frequent ocular diseases that …

Purpose: Genetic variants in genes encoding components of lipid metabolism have been
associated with AMD. The aims of this study were to evaluate the relation of these genetic …

Our eyes are windows to the world and to our soul. The approach to them offers an
incredible space for conducting research to learn more about gender differences in ocular …

Ageing of the retina is associated with the gradual accumulation of basal deposits and the
formation of drusen. However, in some individuals this process is exacerbated and causes …

Topic Though lipid and cholesterol dyshomeostasis is thought to contribute to the
pathogenesis of age-related macular degeneration (AMD), there is no consensus regarding …

Purpose To determine the frequency of the genotypes of single nucleotide polymorphisms
(SNPs) in the gene encoding cholesteryl ester transfer protein (CETP) and their associations …