The rapid generation of molecular complexity from simple starting materials is of paramount
importance in synthetic chemistry. The unique combination of high reactivity and high …

Covering: 2012. Previous review: Nat. Prod. Rep., 2013, 30, 237–323. This review covers
the literature published in 2012 for marine natural products, with 1035 citations (673 for the …

We report herein an operationally simple method for the direct conversion of benzylic C–H
groups to C–F. We show that visible light can activate diarylketones to abstract a benzylic …

Natural products have historically been a rich source of diverse chemical matter with
numerous biological activities, and have played an important role in drug discovery in many …

Cascade (domino) reactions have an unparalleled ability to generate molecular complexity
from relatively simple starting materials; these transformations are particularly appealing …

A 2-pyridone ring is a frequently occurring subunit in natural products, biologically active
compounds, and pharmaceutical targets. Thus, the selective synthesis of substituted 2 …

Covering: July 2012 to June 2015. Previous review: Nat. Prod. Rep., 2013, 30, 869–915 The
structurally diverse imidazole-, oxazole-, and thiazole-containing secondary metabolites are …

Covering: 2006 to 2015 C–H functionalization remains one of the frontier challenges in
organic chemistry and drives quite an active area of research. It has recently been applied in …

The preceding four decades have witnessed a major expansion in the field of free-radical
assisted reactions, as they are becoming a key tool in organic, polymer and complex natural …

Investigation of the marine sponge Agelas dispar MeOH fractions using feature-based
molecular networking, dereplication, and isolation led to the discovery of new bromopyrrole …