Chitosan is a product of the deacetylation of chitin, which is widely found in nature. Chitosan
is insoluble in water and most organic solvents, which seriously limits both its application …

In the past few decades, polymeric nanocarriers have been recognized as promising tools
and have gained attention from researchers for their potential to efficiently deliver bioactive …

Chitin, as the main component of the exoskeleton of Arthropoda, is a highly available natural
polymer that can be processed into various value-added products. Its most important …

Cellular delivery of biomacromolecules is vital to medical research and therapeutic
development. Cationic polymers are promising and affordable candidate vehicles for these …

Polymeric drug delivery technology, which allows for medicinal ingredients to enter a cell
more easily, has advanced considerably in recent decades. Innovative medication delivery …

Early antitumor therapy is an important determinant of survival in patients with cancer.
Utilization of specific pathological states, such as hypoxia, greatly promotes the …

The conventional Drug Delivery System (DDS) has limitations such as leakage of the drug,
toxicity to normal cells and loss of drug efficiency, while the stimuli-responsive DDS is non …

Lacking nano-systems for precisely codelivering the chemotherapeutics paclitaxel (PTX)
and the natural P-glycoprotein (P-gp) inhibitor, quercetin (QU), into cancer cells and …

Chitosan is a non-toxic biological material, but chitosan is insoluble in water, which hinders
the development and utilization of chitosan. Chitosan derivatives N-2-Hydroxypropyl …

Kupffer cells (KCs) are resident macrophages of the liver purposefully attached to sinusoidal
endothelial cells in the sinusoidal domain of the liver to offer a first line of innate immunity …