Role of resveratrol in prevention and therapy of cancer: preclinical and clinical studies

BB Aggarwal, A Bhardwaj, RS Aggarwal… - Anticancer …, 2004 - ar.iiarjournals.org
Resveratrol, trans-3, 5, 4'-trihydroxystilbene, was first isolated in 1940 as a constituent of the
roots of white hellebore (Veratrum grandiflorum O. Loes), but has since been found in …

Anticancer activity of stilbene‐based derivatives

B De Filippis, A Ammazzalorso, M Fantacuzzi… - …, 2017 - Wiley Online Library
Stilbene is an abundant structural scaffold in nature, and stilbene‐based compounds have
been widely reported for their biological activity. Notably,(E)‐resveratrol and its natural …

Lewis Base-Catalyzed Dynamic Kinetic Asymmetric Transformation of Racemic Chlorosilanes en Route to Si-Stereogenic Silylethers

T Hu, Y Zhang, W Wang, Q Li, L Huang… - Journal of the …, 2024 - ACS Publications
Enantiopure Si-stereogenic organosilanes are highly valued in the fields of organic
synthesis, development of advanced materials, and drug discovery. However, they are not …

Epigenetic multiple ligands: mixed histone/protein methyltransferase, acetyltransferase, and class III deacetylase (sirtuin) inhibitors

A Mai, D Cheng, MT Bedford, S Valente… - Journal of medicinal …, 2008 - ACS Publications
A number of new compounds bearing two ortho-bromo-and ortho, ortho-dibromophenol
moieties linked through a saturated/unsaturated, linear/(poly) cyclic spacer (compounds 1 …

A one-pot ultrasound-assisted water extraction/cyclodextrin encapsulation of resveratrol from Polygonum cuspidatum

S Mantegna, A Binello, L Boffa, M Giorgis, C Cena… - Food Chemistry, 2012 - Elsevier
The ultrasound-assisted extraction (UAE) of resveratrol and other polyphenols from
Polygonum cuspidatum has been carried out with the aim of developing an efficient and eco …

Synthesis and biological evaluation of a library of resveratrol analogues as inhibitors of COX-1, COX-2 and NF-κB

SS Kang, M Cuendet, DC Endringer, VL Croy… - Bioorganic & medicinal …, 2009 - Elsevier
Resveratrol (4, 3′, 5′-trihydroxystilbene) is a naturally occurring antioxidant that inhibits
cyclooxygenase-1 (COX-1), cyclooxygenase-2 (COX-2) and the transcription factor NF-κB. A …

Evaluation of novel conjugated resveratrol polymeric nanoparticles in reduction of plasma degradation, hepatic metabolism and its augmentation of anticancer activity …

YJ Yee, HAE Benson, CR Dass, Y Chen - International Journal of …, 2022 - Elsevier
Resveratrol (RSV) is a natural product with multiple biological benefits including anticancer
properties. Unfortunately, its biological benefits are limited by its low bioavailability and rapid …

The antioxidant effect of imine resveratrol analogues

J Lu, C Li, YF Chai, DY Yang, CR Sun - Bioorganic & medicinal chemistry …, 2012 - Elsevier
Twenty five Imine resveratrol analogues (IRAs) were synthesized, replacing the CC bond in
resveratrol with CN bond, as well as substitution modifications on aromatic rings. Radical …

Oxidized resveratrol metabolites as potent antioxidants and xanthine oxidase inhibitors

OG Agbadua, N Kúsz, R Berkecz, T Gáti, G Tóth… - Antioxidants, 2022 - mdpi.com
Resveratrol is a well-known natural polyphenol with a plethora of pharmacological activities.
As a potent antioxidant, resveratrol is highly oxidizable and readily reacts with reactive …

An improved synthesis of resveratrol

A Farina, C Ferranti, C Marra - Natural product research, 2006 - Taylor & Francis
In this article we report an improved total synthesis of resveratrol, increasing the overall yield
from 22 to 71%. The synthesis reported in our previous publication was made up of two …