Side effects of statins: from pathophysiology and epidemiology to diagnostic and therapeutic implications

M Ruscica, N Ferri, M Banach, CR Sirtori… - Cardiovascular …, 2022 - academic.oup.com
Abstract Treatment with statins, inhibitors of 3-hydroxy-3-methylglutaryl-coenzyme A
reductase, has proven beneficial preventive effects on cardiovascular events. However …

[HTML][HTML] Beyond statins: New pharmacological targets to decrease LDL-cholesterol and cardiovascular events

E Raschi, M Casula, AFG Cicero, A Corsini… - Pharmacology & …, 2023 - Elsevier
The pharmacological treatment of dyslipidemia, a major modifiable risk factor for developing
atherosclerotic cardiovascular disease (ASCVD), remains a debated and controversial …

[HTML][HTML] PoLA/CFPiP/PCS/PSLD/PSD/PSH guidelines on diagnosis and therapy of lipid disorders in Poland 2021

M Banach, P Burchardt, K Chlebus… - Archives of Medical …, 2021 - ncbi.nlm.nih.gov
Moreover, over the last few years the approach to treatment of patients with a high
cardiovascular risk has totally changed from treatment aimed at a specific risk factor (ie …

[HTML][HTML] Bempedoic acid in the management of lipid disorders and cardiovascular risk. 2023 position paper of the International Lipid Expert Panel (ILEP)

M Banach, PE Penson, M Farnier, Z Fras… - Progress in …, 2023 - Elsevier
Cardiovascular disease (CVD) is a chronic non-communicable disease (NCD) and the
predominant cause of morbidity and mortality worldwide. Substantial reductions in the CVD …

Advantages and disadvantages of inclisiran: a small interfering ribonucleic acid molecule targeting PCSK9—a narrative review

I Merćep, N Friščić, D Strikić… - Cardiovascular …, 2022 - Wiley Online Library
As dyslipidemias remain one of the main risk factors for developing cardiovascular disease,
the question of maintaining optimal lipid levels with pharmacotherapy remains a subject of …

Causes, Angiographic Characteristics, and Management of Premature Myocardial Infarction: JACC State-of-the-Art Review

LS Rallidis, I Xenogiannis, ES Brilakis… - Journal of the American …, 2022 - jacc.org
Among patients presenting with acute myocardial infarction (AMI), the proportion of young
individuals has increased in recent years. Although coronary atherosclerosis is less …

Step‐by‐step diagnosis and management of the nocebo/drucebo effect in statin‐associated muscle symptoms patients: a position paper from the International Lipid …

PE Penson, E Bruckert, D Marais… - Journal of cachexia …, 2022 - Wiley Online Library
Statin intolerance is a clinical syndrome whereby adverse effects (AEs) associated with
statin therapy [most commonly statin‐associated muscle symptoms (SAMS)] result in the …

Intensive statin therapy versus upfront combination therapy of statin and ezetimibe in patients with acute coronary syndrome: a propensity score matching analysis …

J Lewek, J Niedziela, P Desperak… - Journal of the …, 2023 - Am Heart Assoc
Background We aimed to compare statin monotherapy and upfront combination therapy of
statin and ezetimibe in patients with acute coronary syndromes (ACSs). Methods and …

[HTML][HTML] A look to the past–what has had the biggest impact on lipids in the last four decades? A personal perspective

M Banach, S Surma - Archives of Medical Science: AMS, 2023 - ncbi.nlm.nih.gov
We live in interesting times, when we finally have the possibility of effective treatment of
patients with lipid disorders, and in fact with numerous effective drugs available, it should be …

[HTML][HTML] Dyslipidemia management for primary prevention of cardiovascular events: Best in-clinic practices

N Thongtang, R Sukmawan, EJB Llanes… - Preventive Medicine …, 2022 - Elsevier
Dyslipidemia is a fundamental risk factor for cardiovascular diseases (CVDs) and can
worsen the prognosis, if unaddressed. Lipid guidelines are still evolving as dyslipidemia is …