Determinants of peroxisome membrane dynamics

RE Carmichael, M Schrader - Frontiers in Physiology, 2022 - frontiersin.org
Organelles within the cell are highly dynamic entities, requiring dramatic morphological
changes to support their function and maintenance. As a result, organelle membranes are …

Peroxisomal ROS control cytosolic Mycobacterium tuberculosis replication in human macrophages

E Pellegrino, B Aylan, C Bussi, A Fearns… - Journal of Cell …, 2023 - rupress.org
Peroxisomes are organelles involved in many metabolic processes including lipid
metabolism, reactive oxygen species (ROS) turnover, and antimicrobial immune responses …

Fission impossible (?)—new insights into disorders of peroxisome dynamics

RE Carmichael, M Islinger, M Schrader - Cells, 2022 - mdpi.com
Peroxisomes are highly dynamic and responsive organelles, which can adjust their
morphology, number, intracellular position, and metabolic functions according to cellular …

PEX11β and FIS1 cooperate in peroxisome division independently of mitochondrial fission factor

TA Schrader, RE Carmichael, M Islinger… - Journal of Cell …, 2022 - journals.biologists.com
Peroxisome membrane dynamics and division are essential to adapt the peroxisomal
compartment to cellular needs. The peroxisomal membrane protein PEX11β (also known as …

Transforming Growth Factor-β1 Regulates Peroxisomal Genes/Proteins via Smad Signaling in Idiopathic Pulmonary Fibrosis Fibroblasts and Transgenic Mouse …

G Oruqaj, S Karnati, LK Kotarkonda, E Boateng… - The American Journal of …, 2023 - Elsevier
Idiopathic pulmonary fibrosis (IPF) is a chronic human disease with persistent destruction of
lung parenchyma. Transforming growth factor-β1 (TGF-β1) signaling plays a pivotal role in …

Organelle membrane extensions in mammalian cells

RE Carmichael, DM Richards, HD Fahimi, M Schrader - Biology, 2023 - mdpi.com
Simple Summary Within cells, there are numerous compartments called 'organelles' that
perform a range of specialised functions required to support life. Organelles are constantly …

Protein Kinase C positively regulates peroxisome biogenesis by promoting peroxisome-endoplasmic reticulum interaction

A Borisyuk, CM Howman, S Pattabiraman… - bioRxiv, 2025 - biorxiv.org
Peroxisomes carry out a diverse set of metabolic functions, including oxidation of very long-
chained fatty acids, degradation of D-amino acids and hydrogen peroxide, and bile acid …

Immunolabeling for Detection of Endogenous and Overexpressed Peroxisomal Proteins in Mammalian Cells

TA Schrader, RE Carmichael, M Schrader - Peroxisomes: Methods and …, 2023 - Springer
Peroxisomes are dynamic subcellular organelles in mammals, playing essential roles in
cellular lipid metabolism and redox homeostasis. They perform a wide spectrum of functions …

Generation of reporter cell lines for endogenous expression analysis of peroxisomal proteins

BSC Silva, TA Schrader, M Schrader… - … : Methods and Protocols, 2023 - Springer
Peroxisomes are multifunctional, ubiquitous, and dynamic organelles. They are responsible
for diverse metabolic and physiological functions and communicate with other organelles …

Controlling peroxisome-ER contacts–Molecular mechanisms to regulate peroxisome tethering and distribution

S Kors - 2022 - ore.exeter.ac.uk
Peroxisomes are small, single membrane bound organelles with key roles in cellular lipid
and hydrogen peroxide metabolism. They contribute to a wide range of metabolic processes …