Obesity-related oxidative stress, the imbalance between pro-oxidants and antioxidants (eg,
nitric oxide), has been linked to metabolic and cardiovascular disease, including endothelial …

Activin A receptor type I (ACVR1) encodes for a bone morphogenetic protein type I receptor
of the TGFβ receptor superfamily. It is involved in a wide variety of biological processes …

We examined the effects of betaine, an endogenous and dietary methyl donor essential for
the methionine-homocysteine cycle, on oxidative stress, inflammation, apoptosis, and …

Non-alcoholic fatty liver disease (NAFLD) is a chronic liver disease characterized by
excessive lipid deposition. Lipid metabolism disturbances are possibly associated with …

Background Malnutrition resulting from protein and calorie deficiency continues to be a
major concern worldwide especially in developing countries. Specific deficiencies in the …

Chronic liver disease (CLD) affects a significant portion of the global population, leading to a
substantial number of deaths each year. Distinct forms like non-alcoholic fatty liver disease …

Aims Fructose administration induces hepatic oxidative stress, insulin resistance,
inflammatory and metabolic changes. We tested their potential pathogenic relationship and …

As innovations in global agricultural production and food trading systems lead to major
dietary shifts, high morbidity rates from non-alcoholic fatty liver disease (NAFLD) …

Lipid mediators derived from arachidonic acid (AA) are implicated with the occurrence of
inflammation and oxidative stress. The current knowledge of AA metabolism focuses on …

Liver fibrosis is a pathophysiologic process involving the accumulation of extracellular matrix
proteins as collagen deposition. Advanced liver fibrosis can evolve in cirrhosis, portal …