Methicillin-resistant Staphylococcus aureus: an overview of basic and clinical research

NA Turner, BK Sharma-Kuinkel… - Nature Reviews …, 2019 - nature.com
Methicillin-resistant Staphylococcus aureus (MRSA) is one of the most successful modern
pathogens. The same organism that lives as a commensal and is transmitted in both health …

Staphylococcus aureus Toxins and Their Molecular Activity in Infectious Diseases

D Oliveira, A Borges, M Simões - Toxins, 2018 - mdpi.com
Staphylococcus aureus is a microorganism resident in the skin and nasal membranes with a
dreadful pathogenic potential to cause a variety of community and hospital-acquired …

Staphylococcus aureus bloodstream infections: pathogenesis and regulatory mechanisms

JM Kwiecinski, AR Horswill - Current opinion in microbiology, 2020 - Elsevier
Highlights•Phagocytes play both protective and detrimental roles in containing bloodstream
S. aureus.•S. aureus hijacks the host coagulation system and uses it to bind host …

Clinical Impact of Staphylococcus aureus Skin and Soft Tissue Infections

MS Linz, A Mattappallil, D Finkel, D Parker - Antibiotics, 2023 - mdpi.com
The pathogenic bacterium Staphylococcus aureus is the most common pathogen isolated in
skin-and-soft-tissue infections (SSTIs) in the United States. Most S. aureus SSTIs are caused …

Staphylococcal manipulation of host immune responses

V Thammavongsa, HK Kim, D Missiakas… - Nature Reviews …, 2015 - nature.com
Staphylococcus aureus, a bacterial commensal of the human nares and skin, is a frequent
cause of soft tissue and bloodstream infections. A hallmark of staphylococcal infections is …

The staphylococcal biofilm: adhesins, regulation, and host response

AE Paharik, AR Horswill - Virulence mechanisms of bacterial …, 2016 - Wiley Online Library
The Staphylococcus genus includes a diverse group of commensals that colonize mammals
on the skin or mucous membranes. Some of the best‐known members of this genus, such as …

Staphylococcus aureus α-Toxin: Nearly a Century of Intrigue

BJ Berube, J Bubeck Wardenburg - Toxins, 2013 - mdpi.com
Staphylococcus aureus secretes a number of host-injurious toxins, among the most
prominent of which is the small β-barrel pore-forming toxin α-hemolysin. Initially named …

Staphylococcal and streptococcal superantigen exotoxins

AR Spaulding, W Salgado-Pabón… - Clinical microbiology …, 2013 - Am Soc Microbiol
This review begins with a discussion of the large family of Staphylococcus aureus and beta-
hemolytic streptococcal pyrogenic toxin T lymphocyte superantigens from structural and …

A genomic portrait of the emergence, evolution, and global spread of a methicillin-resistant Staphylococcus aureus pandemic

MTG Holden, LY Hsu, K Kurt, LA Weinert… - Genome …, 2013 - genome.cshlp.org
The widespread use of antibiotics in association with high-density clinical care has driven
the emergence of drug-resistant bacteria that are adapted to thrive in hospitalized patients …

Global epidemiology of community-associated methicillin resistant Staphylococcus aureus (CA-MRSA)

JR Mediavilla, L Chen, B Mathema… - Current opinion in …, 2012 - Elsevier
During the 1990s, various reports of community-associated methicillin-resistant
Staphylococcus aureus (CA-MRSA) infections appeared in the literature, caused by novel …