[HTML][HTML] ME/CFS and Long COVID share similar symptoms and biological abnormalities: road map to the literature

AL Komaroff, WI Lipkin - Frontiers in Medicine, 2023 - frontiersin.org
Some patients remain unwell for months after “recovering” from the acute COVID-19. They
develop persistent fatigue, cognitive problems, headaches, disrupted sleep, myalgias and …

Damage to endothelial barriers and its contribution to long COVID

X Wu, M Xiang, H Jing, C Wang, VA Novakovic, J Shi - Angiogenesis, 2024 - Springer
The world continues to contend with COVID-19, fueled by the emergence of viral variants. At
the same time, a subset of convalescent individuals continues to experience persistent and …

Long COVID manifests with T cell dysregulation, inflammation and an uncoordinated adaptive immune response to SARS-CoV-2

K Yin, MJ Peluso, X Luo, R Thomas, MG Shin… - Nature …, 2024 - nature.com
Long COVID (LC) occurs after at least 10% of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) infections, yet its etiology remains poorly understood. We used …

Increased levels of inflammatory and endothelial biomarkers in blood of long COVID patients point to thrombotic endothelialitis

S Turner, CA Naidoo, TJ Usher… - … in Thrombosis and …, 2024 - thieme-connect.com
The prevailing hypotheses for the persistent symptoms of Long COVID have been narrowed
down to immune dysregulation and autoantibodies, widespread organ damage, viral …

[HTML][HTML] Epstein–Barr virus-acquired immunodeficiency in myalgic encephalomyelitis—Is it present in long COVID?

M Ruiz-Pablos, B Paiva, A Zabaleta - Journal of Translational Medicine, 2023 - Springer
Both myalgic encephalomyelitis or chronic fatigue syndrome (ME/CFS) and long COVID
(LC) are characterized by similar immunological alterations, persistence of chronic viral …

Biomarkers of sustained systemic inflammation and microvascular dysfunction associated with post-COVID-19 condition symptoms at 24 months after SARS-CoV-2 …

LMC Jacobs, MSJN Wintjens, M Nagy… - Frontiers in …, 2023 - frontiersin.org
Introduction Comprehensive studies investigating sustained hypercoagulability, endothelial
function, and/or inflammation in relation to post-COVID-19 (PCC) symptoms with a …

Lung perfusion assessment in children with long‐COVID: A pilot study

DA Pizzuto, D Buonsenso, R Morello… - Pediatric …, 2023 - Wiley Online Library
Background There is increasing evidence that chronic endotheliopathy can play a role in
patients with Post‐Covid Condition (PCC, or Long Covid) by affecting peripheral …

A perspective on how fibrinaloid microclots and platelet pathology may be applied in clinical investigations

E Pretorius, DB Kell - Seminars in Thrombosis and Hemostasis, 2024 - thieme-connect.com
Microscopy imaging has enabled us to establish the presence of fibrin (ogen) amyloid
(fibrinaloid) microclots in a range of chronic, inflammatory diseases. Microclots may also be …

[HTML][HTML] Von Willebrand factor and the thrombophilia of severe COVID-19: in situ evidence from autopsies

J van den Berg, JD Haslbauer, AK Stalder… - Research and Practice …, 2023 - Elsevier
Background COVID-19 is accompanied by a hypercoagulable state and characterized by
microvascular and macrovascular thrombotic complications. In plasma samples from …

Accelerating discovery: A novel flow cytometric method for detecting fibrin (ogen) amyloid microclots using long COVID as a model

S Turner, GJ Laubscher, MA Khan, DB Kell, E Pretorius - Heliyon, 2023 - cell.com
Long COVID has become a significant global health and economic burden, yet there are
currently no established methods or diagnostic tools to identify which patients might benefit …