Primary bile acids serve important roles in cholesterol metabolism, lipid digestion, host-
microbe interactions, and regulatory pathways in the human host. While most bile acids are …

Short-chain fatty acids (SCFAs) are the main metabolites produced by the bacterial
fermentation of dietary fiber, and they play a critical role in the maintenance of intestinal …

Crohn's disease and ulcerative colitis, known together as inflammatory bowel diseases
(IBDs), and celiac disease are the most common disorders affecting not only adults but also …

This review will focus on published human studies on oxidative stress and DNA damage in
inflammatory bowel disease (IBD), both ulcerative colitis and Crohn's disease, assessing …

Antimicrobial peptides (AMPs) is a large family of compounds serving as natural antibiotics,
widely distributed across the organism, mainly in mucus layers. They are designed to …

Environmental triggers is part of five focus areas of the Challenges in IBD research
document, which also includes preclinical human IBD mechanisms, novel technologies …

The global incidence of inflammatory bowel disease (IBD), a group of chronic
gastrointestinal disorders, has been rising. The preponderance of evidence demonstrates …

Objectives Inconsistent findings have been published regarding vitamin D status among
patients with Crohn's disease (CD) and the association with disease severity. We aimed to …

Background: Vitamin deficiency is frequently associated with inflammatory bowel disease
(IBD). Supplementation of vitamins could thus serve as an adjunctive therapy. The present …

Inflammatory Bowel Diseases (IBD) are difficult to model as freshly acquired tissues are
short-lived, provide data as a snapshot in time, and are not always accessible. Many …