The nature and applications of π–π interactions: a perspective

R Thakuria, NK Nath, BK Saha - Crystal Growth & Design, 2019 - ACS Publications
The updated concepts on the nature of π–π interactions and their use in various fields
ranging from crystal engineering to materials science to biochemistry are discussed. This is …

π–π stacking interaction: a nondestructive and facile means in material engineering for bioapplications

T Chen, M Li, J Liu - Crystal Growth & Design, 2018 - ACS Publications
π–π stacking interactions, as a kind of attractive and nondestructive noncovalent interaction,
have been widely explored for the applications in modern chemistry, molecular biology, and …

Controlled release of donepezil intercalated in smectite clays

JK Park, YB Choy, JM Oh, JY Kim, SJ Hwang… - International Journal of …, 2008 - Elsevier
The inorganic–organic hybrid for a drug delivery system was successfully realized by
intercalating donepezil molecules into smectite clays (laponite XLG, saponite, and …

Tip-loaded dissolving microneedles for transdermal delivery of donepezil hydrochloride for treatment of Alzheimer's disease

JY Kim, MR Han, YH Kim, SW Shin, SY Nam… - European Journal of …, 2016 - Elsevier
Donepezil hydrochloride (DPH) is often used in the treatment of Alzheimer's disease. A new
treatment method was developed by encapsulating high DPH content in the tips of …

Molecular interactions of cholinesterases inhibitors using in silico methods: current status and future prospects

MTH Khan - New biotechnology, 2009 - Elsevier
Alzheimer's disease (AD) is a neurodegenerative disorder characterized by a low amount of
acetylcholine (ACh) in hippocampus and cortex. Acetylcholinesterase (AChE) is one of the …

[PDF][PDF] Alzheimer's and current therapeutics: A review

A Panche, S Chandra, AD Diwan… - Asian J Pharm Clin Res, 2015 - researchgate.net
In recent past several efforts have been made to analyze the symptoms, causes, and cure of
Alzheimer's disease (AD) and also to reveal biochemical changes and pathogenesis of the …

Tacrine–melatonin hybrids as multifunctional agents for Alzheimer's disease, with cholinergic, antioxidant, and neuroprotective properties

MI Fernández‐Bachiller, C Pérez… - ChemMedChem …, 2009 - Wiley Online Library
Tacrine–melatonin hybrids are potential multifunctional drugs for Alzheimer's disease that
may simultaneously palliate intellectual deficits and protect the brain against both β‐amyloid …

Phytochemical profile, antioxidant activity, inhibition of acetylcholinesterase and interaction mechanism of the major components of the Piper divaricatum essential oil …

MS de Oliveira, JN da Cruz, SG Silva… - The Journal of …, 2019 - Elsevier
The present study reports the use of supercritical CO 2 at different combinations of
temperature and pressure:(35 and 55)° C, and (100, 300, and 500) bar to obtain fractions of …

Metabolites profiling and cheminformatics bioprospection of selected medicinal plants against the main protease and RNA-dependent RNA polymerase of SARS-CoV …

AA Lanrewaju, AM Enitan-Folami… - Journal of …, 2024 - Taylor & Francis
Despite the existence of some vaccines, SARS-CoV-2 (S-2) infections persist for various
reasons relating to vaccine reluctance, rapid mutation rate, and an absence of specific …

Repurposing drugs and identification of inhibitors of integral proteins (spike protein and main protease) of SARS-CoV-2

FO Shode, ASK Idowu, OJ Uhomoibhi… - Journal of Biomolecular …, 2022 - Taylor & Francis
The outbreak of Coronavirus infection (COVID-19) has prompted the World Health
Organisation (WHO) to declare the outbreak, a Public Health Emergency of International …