A novel oncogene URG4/URGCP and its role in cancer
Oncogenes are mutated form of normal cellular genes called as proto-oncogenes and
conduce to the cancer development process. Despite the fact that so many genes have been …
conduce to the cancer development process. Despite the fact that so many genes have been …
Anti-proliferative and anti-invasive effects of ferulic acid in TT medullary thyroid cancer cells interacting with URG4/URGCP
Abstract Ferulic acid (4-hydroxy-3-methoxycinnamic acid; FA), a common dietary plant
phenolic compound, is abundant in fruits and vegetables. The aim of present study is to …
phenolic compound, is abundant in fruits and vegetables. The aim of present study is to …
Role of AHR, NF-kB and CYP1A1 crosstalk with the X protein of Hepatitis B virus in hepatocellular carcinoma cells
G Celik-Turgut, N Olmez, T Koc, O Ozgun-Acar… - Gene, 2023 - Elsevier
In this study, it was aimed to elucidate the interaction between aryl hydrocarbon receptor
(AHR), nuclear factor-kappa B (NF-kB), and cytochrome P4501A1 (CYP1A1) with hepatitis B …
(AHR), nuclear factor-kappa B (NF-kB), and cytochrome P4501A1 (CYP1A1) with hepatitis B …
[HTML][HTML] URGCP promotes non-small cell lung cancer invasiveness by activating the NF-κB-MMP-9 pathway
Invasion and metastasis are main traits of tumor progression and responsible for the poor
prognosis of advanced non-small cell lung cancer (NSCLC). The molecular mechanisms …
prognosis of advanced non-small cell lung cancer (NSCLC). The molecular mechanisms …
Temozolomide may induce cell cycle arrest by interacting with URG4/URGCP in SH-SY5Y neuroblastoma cells
Temozolomide (TMZ) is an alkylating drug used usually in glioma treatment by inducing the
apoptosis in glioma cell. The aim of the study is to investigate the anticancer mechanism of …
apoptosis in glioma cell. The aim of the study is to investigate the anticancer mechanism of …
URG4 mediates cell proliferation and cell cycle in osteosarcoma via GSK3β/β-catenin/cyclin D1 signaling pathway
Y Liu, Y Xi, G Chen, X Wu, M He - Journal of Orthopaedic Surgery and …, 2020 - Springer
Background Osteosarcoma is one of the most common malignant bone tumors with the
annual global incidence of approximately four per million. Upregulated gene 4 (URG4) …
annual global incidence of approximately four per million. Upregulated gene 4 (URG4) …
Differential expression of store-operated calcium-and proliferation-related genes in hepatocellular carcinoma cells following TRPC1 ion channel silencing
TRPC1 and store-operated Ca 2+(SOC) entry have previously been associated with
hepatocellular carcinoma cell proliferation. The aim of the study was to determine genes and …
hepatocellular carcinoma cell proliferation. The aim of the study was to determine genes and …
Identification of intracellular pathways through which TGF-β1 upregulates URG-4/URGCP gene expression in hepatoma cells
Aims Up-regulated gene 4 (URG-4/URGCP) was strongly expressed in Hepatitis B infected
liver and correlated with HBxAG (Hepatitis B x Antigen) protein and found to promote …
liver and correlated with HBxAG (Hepatitis B x Antigen) protein and found to promote …
TNF-α Induces URG-4/URGCP gene expression in hepatoma cells through starvation dependent manner
URG-4/URGCP is a gene that may be associated with the onset of tumorigenesis and cell
cycle regulation. In the literature, there is no study about inflammatory cytokine-mediated …
cycle regulation. In the literature, there is no study about inflammatory cytokine-mediated …
Downregulation of miR-16 via URGCP pathway contributes to glioma growth
L Hong, O Qing, Z Ji, Z Chengqu, C Ying, C Hao… - Scientific reports, 2017 - nature.com
Experimental and clinical evidence points to a critical role of Upregulator of cell proliferation
(URGCP/URG4) in controlling the progression of multiple tumors. However, the oncogenic …
(URGCP/URG4) in controlling the progression of multiple tumors. However, the oncogenic …